76716-21-7

Basic information

• Product Name: 1-methyl-butylamine hydrochloride
• CAS NO: 76716-21-7
• Molecular Weight: 123.626
• Mol File: 76716-21-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-methyl-butylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-butylamine hydrochloride(76716-21-7)
• EPA Substance Registry System: 1-methyl-butylamine hydrochloride(76716-21-7)

Safety Data

• Hazardous Substances Data: 76716-21-7(Hazardous Substances Data)

Usage

Type of compound

Hydrochloride salt of 1-methyl-butylamine

Structure

Primary amine with a methyl group attached to the nitrogen atom

Uses

Synthesis of pharmaceuticals, agrochemicals, and other organic compounds; precursor to industrial chemicals; reagent in organic chemistry reactions; key intermediate in production of surfactants and corrosion inhibitors

Physical properties

Colorless to pale yellow liquid; strong ammonia-like odor; soluble in water

Upstream product

• 146039-15-8 1-Methyl-butyl-phosphorimidic acid triethyl ester 
• 627-19-0 1-Pentyne 
• 109-66-0 pentane 
• 107-87-9 2-Pentanone 
• 625-30-9 2-pentylamine 
• 109-67-1 1-penten 
• 107-81-3 2-bromopentane 
• 73746-39-1 2-pentylazide 
• 4551-09-1 pentan-2-yl methanesulfonate 
• 6032-29-7 (+/-)-2-pentanol 
• 102095-59-0 C₁₄H₃₀NO₅P 
• 76716-19-3 C₁₇H₂₂NOP 
• 85231-72-7 (1-Methyl-butyl)-phosphoramidic acid diethyl ester 

Downstream Products

• 101689-14-9 C₁₅H₂₀F₃NO₂ 
• 512847-56-2 [4-(2,4-dichloro-phenyl)-3-nitro-pyridin-2-yl]-(1-methyl-butyl)-amine 

Relevant articles and documents

Cerium-Catalyzed C-H Functionalizations of Alkanes Utilizing Alcohols as Hydrogen Atom Transfer Agents

Modern photoredox catalysis has traditionally relied upon metal-to-ligand charge-transfer (MLCT) excitation of metal polypyridyl complexes for the utilization of light energy for the activation of organic substrates. Here, we demonstrate the catalytic application of ligand-to-metal charge-transfer (LMCT) excitation of cerium alkoxide complexes for the facile activation of alkanes utilizing abundant and inexpensive cerium trichloride as the catalyst. As demonstrated by cerium-catalyzed C-H amination and the alkylation of hydrocarbons, this reaction manifold has enabled the facile use of abundant alcohols as practical and selective hydrogen atom transfer (HAT) agents via the direct access of energetically challenging alkoxy radicals. Furthermore, the LMCT excitation event has been investigated through a series of spectroscopic experiments, revealing a rapid bond homolysis process and an effective production of alkoxy radicals, collectively ruling out the LMCT/homolysis event as the rate-determining step of this C-H functionalization.

Development of an in situ-Product Crystallization (ISPC)-Concept to Shift the Reaction Equilibria of Selected Amine Transaminase-Catalyzed Reactions

The synthesis of enantiopure amines via amine transaminases involves several challenges including unfavorable reaction equilibria and product inhibition. Described here is a non-catalytic approach to overcome such problems by using an in situ-product crystallization (ISPC) to selectively remove a targeted product amine from an amine transaminase-catalyzed reaction. The continuous removal of the product amine from its reaction solution as a barely soluble salt effectively yields a displacement of the reaction equilibrium towards the products and facilitates a simple downstream processing approach via filtration. The targeted product amine is eventually obtained from the salt, while the counterion compound can be easily recycled.

TRIETHYL PHOSPHITE IN ORGANIC SYNTHESIS. A FACILE, ONE-POT CONVERSION OF ALCOHOLS INTO AMINES

General protocols for converting primary, secondary, and tertiary alcohols into the corresponding primary amines are presented.