76745-20-5Relevant articles and documents
BIFUNCTIONAL CHIRAL SYNTHONS VIA MICROBIOLOGICAL METHODS. 2. OPTICALLY-ACTIVE α-HYDROXY ALDEHYDES.
Takaishi, Yoshihisa,Yang, Yuh-Lin,DiTullio, Dennis,Sih, Charles J.
, p. 5489 - 5492 (1982)
A versatile chemical-microbiological approach has been developed for the preparation of chiral α-hydroxy aldehydes via stereoselective reduction of the corresponding α-keto thioacetals or via optical resolution of the racemic α-acetoxy esters.
A PRACTICAL METHOD FOR THE PRODUCTION OF METHYL 5(S)-BENZOYLOXY-5-FORMYLPENTANOATE - A KEY INTERMEDIATE IN THE SYNTHESIS OF LEUKOTRIENE B4
Kornilov, A. M.,Furmanova, M. V.,Sorochinskii, A. E.,Kukhar', V. P.
, p. 1067 - 1069 (2007/10/02)
Catalytic epoxidation of methyl 7-hydroxy-5(E)-heptenoate by the Sharpless method gave optically pure (5R,6R)-methyl 5,6-epoxy-7-hydroxyheptanoate, in which regioselective opening of the epoxide ring by benzoic acid with the assistance of titanium tetrais
OPTICALLY ACTIVE PROPARGYLIC ALCOHOLS FROM D-XYLOSE USEFUL PRECURSORS FOR LTB4 SYNTHESIS
Pianetti, P.,Rollin, P.,Pougny, J. R.
, p. 5853 - 5856 (2007/10/02)
Using D-Xylose as a source of chirality at C-5 and C-12 in LTB4, an efficient synthesis of the optically active propargylic alcohols A and B, chiral precursors for the LTB4 synthesis, has been achieved.