768-49-0

Basic information

• Product Name: 2-METHYL-1-PHENYLPROPENE
• Synonyms: ISOCROTYLBENZENE;(2-METHYLPROPENYL)BENZENE;2-METHYL-1-PHENYL-1-PROPENE;2-METHYL-1-PHENYLPROPENE;(2-methyl-1-propenyl)-benzen;(2-Methyl-1-propenyl)benzene;1,1-Dimethyl-2-phenylethylene;1-Phenyl-2-methylpropene
• CAS NO: 768-49-0
• Molecular Formula: C₁₀H₁₂
• Molecular Weight: 132.2
• EINECS: 212-194-6
• Product Categories: Propanes/propenes
• Mol File: 768-49-0.mol
• Article Data: 141

Chemical Properties

• Melting Point: −50-−48 °C(lit.)
• Boiling Point: 187-188 °C(lit.)
• Flash Point: 138 °F
• Appearance: /
• Density: 0.901 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.849mmHg at 25°C
• Refractive Index: n20/D 1.539(lit.)
• Storage Temp.: 2-8°C
• BRN: 1902046
• CAS DataBase Reference: 2-METHYL-1-PHENYLPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1-PHENYLPROPENE(768-49-0)
• EPA Substance Registry System: 2-METHYL-1-PHENYLPROPENE(768-49-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN 3295 3/PG 3
• WGK Germany: 3
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 768-49-0(Hazardous Substances Data)

Usage

Uses

2-Methyl-1-phenyl-1-propene has been used in the preparation of 2-bromo-2-methyl-1-phenylpropan-1-ol and 1-bromo-2-methyl-1-phenylpropan-2-ol.

Synthesis Reference(s)

Journal of the American Chemical Society, 111, p. 3069, 1989 DOI: 10.1021/ja00190a053Tetrahedron Letters, 25, p. 271, 1984 DOI: 10.1016/S0040-4039(00)99859-9The Journal of Organic Chemistry, 55, p. 5619, 1990 DOI: 10.1021/jo00308a021

InChI:InChI=1/C10H12/c1-9(2)8-10-6-4-3-5-7-10/h3-8H,1-2H3

Upstream product

• 75-44-5 phosgene 
• 60-29-7 diethyl ether 
• 515-40-2 neophyl chloride 
• 100-86-7 2-Methyl-1-phenyl-2-propanol 
• 611-69-8 rac-2-methyl-1-phenylpropan-1-ol 
• 33950-46-8 1-phenyl-2,2-dimethyl-1,3-propanediol 
• 23985-59-3 3-hydroxy-2,2-dimethyl-3-phenylpropanoic acid 
• 78-84-2 isobutyraldehyde 
• 676-54-0 ethyl sodium 
• 109-66-0 pentane 
• 591-50-4 iodobenzene 
• 119441-90-6 (2-methylprop-1-en-1-yl)zinc(II) chloride 
• 119441-87-1 C₆H₁₂BBrO₂ 
• 119441-89-3 (E)-(2-bromoethenyl)diisopropoxyborane 

Downstream Products

• 52117-13-2 N-(1,1-dimethyl-2-phenyl-ethyl)-formamide 
• 6052-53-5 3-Methyl-4-phenyl-3-butensaeure 
• 10152-58-6 2,2-dimethyl-3-phenyloxirane 
• 10269-25-7 4-methyl-5-phenyl-1,2-dithiole-3-thione 
• 538-93-2 1-phenyl-2-methylpropane 
• 1678-98-4 isobutylcyclohexane 
• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 20907-13-5 2-methyl-1-phenylpropane-1,2-diol 
• 35293-36-8 2,2,3,3-tetramethyl-1,4-diphenyl-butane 
• 344306-81-6 1,1-dimethyl-2,3-diphenyl-cyclopropane 
• 7653-94-3 1,1-dimethyl-2-phenylcyclopropane 
• 5912-93-6 1-bromo-2-methyl-1-phenyl-1-propene 
• 69278-45-1 2-Methoxy-2-methyl-1-phenyl-propane 
• 102957-47-1 <1',2'-bis<(1-methoxy-1-methyl)ethyl>ethane-1',2'-diyl>bisbenzene 

Relevant articles and documents

Method for synthesizing alkyl olefin through coupling of double-bond carbon-hydrogen bond and saturated carbon-hydrogen bond

The invention discloses a method for synthesizing alkyl olefin through coupling of a double-bond carbon-hydrogen bond and a saturated carbon-hydrogen bond. According to to the method, one-pot reactionis implemented on olefin and sulfoxide in the presence of ferric salt and hydrogen peroxide to generate alkyl olefin; in the method, sulfoxide is simultaneously used as a hydrocarbylation reagent anda solvent of olefin, and a reaction product is alkyl olefin from sulfoxide alkyl coupled with olefin carbon atoms, so that an olefin carbon chain is increased; the reaction conditions are mild, the selectivity is good, the yield is high, and industrial production is facilitated.

Method for hydrocarbylation synthesis of trisubstituted and tetrasubstituted olefins from non-terminal olefins

The invention discloses a method for hydrocarbylation synthesis of trisubstituted and tetrasubstituted olefins from non-terminal olefins, wherein the method comprises the steps: carrying out hydrocarbylation reaction on the non-terminal olefins and sulfoxide in the presence of ferric salt and hydrogen peroxide, carrying out one-pot reaction on disubstituted non-terminal olefins to generate the trisubstituted olefins, and carrying out one-pot reaction on the trisubstituted non-terminal olefins to generate the tetrasubstituted olefins. In the method, sulfoxide is simultaneously used as a hydrocarbylation reagent and a solvent of olefins, and one more hydrocarbyl substituent is added to a reaction product compared with a double-bond carbon atom of a reactant, so that an olefin carbon chain isincreased; the reaction conditions are mild, the selectivity is good, the yield is high, and industrial production is facilitated.

Unexpected Nickel Complex Speciation Unlocks Alternative Pathways for the Reactions of Alkyl Halides with dppf-Nickel(0)

The mechanism of the reactions between dppf-Ni0 complexes and alkyl halides has been investigated using kinetic and mechanistic experiments and DFT calculations. The active species is [Ni(κ2-dppf)(κ1-dppf)], which undergoes a halide abstraction reaction with alkyl halides and rapidly captures the alkyl radical that is formed. The rates of the reactions of [Ni(COD)(dppf)] with alkyl halides and the yields of prototypical nickel-catalyzed Kumada cross-coupling reactions of alkyl halides are shown to be significantly improved by the addition of free dppf ligand.