7681-84-7

Basic information

• Product Name: Tetrahydro-2-furancarboxaldehyde
• Synonyms: Tetrahydro-2-Furancarboxaldehyde ;2-Formyltetrahydrofuran;Tetrahydrofurfural;tetrahydrofuran-2-carboxaldehyde;oxolane-2-carbaldehyde
• CAS NO: 7681-84-7
• Molecular Formula: C₅H₈O₂
• Molecular Weight: 100.12
• Mol File: 7681-84-7.mol
• Article Data: 88

Chemical Properties

• Boiling Point: 142°C (estimate)
• Flash Point: 146.33°C
• Appearance: /
• Density: 1.0874
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.4366 (estimate)
• CAS DataBase Reference: Tetrahydro-2-furancarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydro-2-furancarboxaldehyde(7681-84-7)
• EPA Substance Registry System: Tetrahydro-2-furancarboxaldehyde(7681-84-7)

Safety Data

• RIDADR: 1993
• HazardClass: 3
• PackingGroup: Ⅲ
• Hazardous Substances Data: 7681-84-7(Hazardous Substances Data)

Usage

Description

Tetrahydro-furan-2-carbaldehyde is a useful research chemical for organic synthesis and other chemical processes. A tetrahydrofurfuryl derivative for use as flavour in foods.

Uses

Tetrahydro-2-furancarboxaldehyde is an aldehyde derivative and can be used as a pharmaceutical intermediate.

InChI:InChI=1/C11H12O2S/c1-2-11(12)13-8-9-14-10-6-4-3-5-7-10/h2-7H,1,8-9H2

Upstream product

• 97-99-4 Tetrahydrofurfuryl alcohol 
• 5631-95-8 2,3-dichlorotetrahydro-2H-pyran 
• 4795-29-3 TETRAHYDROFURFURYLAMINE 
• 68836-19-1 5-bromo-3-(methylthio)-1,4-diphenyl-1,2,4-triazolium bromide 
• 1972-28-7 diethylazodicarboxylate 
• 1191-99-7 2,3-dihydro-2H-furan 
• 201230-82-2 carbon monoxide 
• 110-87-2 3,4-dihydro-2H-pyran 
• 5331-61-3 gem-diacetate de tetrahydrofurfural 
• 1708-29-8 2,5-dihydrofuran 
• 146943-47-7 2,5-dihydroxy-valeraldehyde 
• 2786-02-9 2-lithiofuran 
• 98-01-1 furfural 
• 613-75-2 (furan-2-yl)methylene diacetate 

Downstream Products

• 117043-44-4 5-tetrahydro[2]furyl-imidazolidine-2,4-dione 
• 91141-80-9 tetrahydro-furan-2-carbaldehyde-(2,4-dinitro-phenylhydrazone) 
• 90199-05-6 4-tetrahydrofuran-2-yl-but-3-en-2-one 
• 22170-09-8 2-(dibutoxymethyl)tetrahydrofuran 
• 23247-31-6 (E)-tetrahydrofuran-2-carbaldehyde oxime 
• 94489-14-2 2-(hydroxy-tetrahydrofuran-2-yl-methyl)-tetrahydro-furan-2-carbaldehyde 
• 75955-21-4 2-(4-Methylpiperazinomethylene)tetrahydrofuran 
• 76652-05-6 2-(dipropoxymethyl)tetrahydrofuran 
• 33964-71-5 1-(2-tetrahydrofuryl)-1-pentanol 
• 33964-71-5 1-(2-tetrahydrofuryl)-1-pentanol 
• 124890-93-3 (R,S)-(E)-3-(2-Tetrahydrofuryl)propenoic acid ethyl ester 
• 64935-82-6 2-(2'-tetrahydrofuryl)-1,3-dioxepane 
• 78749-70-9 3,9-Bis-(tetrahydro-furan-2-yl)-2,4,8,10-tetraoxa-spiro[5.5]undecane 
• 78749-69-6 5-ethyl-5-hydroxymethyl-2-(2-tetrahydrofuryl)-1,3-dioxane 

Relevant articles and documents

Low-pressure Selective Hydroformylation of 2,3- and 2,5-Dihydrofuran with a Rhodium Catalyst. Unexpected Influence of the Auxiliary Ligand Tris(o-t-butylphenyl) Phosphite

Hydroformylation of 2,3- and 2,5-dihydrofuran has been achieved in excellent yields and good selectivities under mild conditions using 2(cod)2> and suitable auxiliary ligands (cod = cyclo-octa-1,5-diene).

RING CONTRACTION IN THE REACTION OF CYCLIC OLEFINS WITH IODINE(III)-CONTAINING REAGENTS

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Aqueous phase hydrogenation of furfural to tetrahydrofurfuryl alcohol over Pd/UiO-66

A Pd/UiO-66 catalyst was synthesized with well-dispersed Pd nanoparticles. The obtained catalyst was tested in the hydrogenation of furfural to tetrahydrofurfuryl alcohol in various solvents, Water was found to be the most suitable solvent. Pd/UiO-66 exhibited much higher activity than Pd/SiO2 and Pd/γ-Al2O3, completely converting furfural to tetrahydrofurfuryl alcohol with 100% selectivity under mild conditions. The hydrogenation of C[dbnd]O moiety in tetrahydrofurfural was rate-determining step. Static adsorption measurement indicated that the adsorption of furfural on UiO-66 was significantly stronger than that on SiO2 or γ-Al2O3, suggesting that the adsorption play an important role in the gas-liquid-solid furfural hydrogenation reaction.

Intermolecular C-O Bond Formation with Alkoxyl Radicals: Photoredox-Catalyzed α-Alkoxylation of Carbonyl Compounds

Due to the high reactivity of alkoxyl (RO·) radicals and their propensity to easily undergo β-scission or Hydrogen Atom Transfer (HAT) reactions, intermolecular alkoxylations involving RO· radicals are barely described. We report herein for the first time the efficient intermolecular trapping of alkoxyl radicals by silyl enol ethers. This photoredox-mediated protocol enables the introduction of both structurally simple and more complex alkoxy groups into a wide range of ketones and amides.