769159-85-5

Basic information

• Product Name: 4-cyclopropyl-1-fluoro-2-nitrobenzene
• Synonyms: 4-cyclopropyl-1-fluoro-2-nitrobenzene
• CAS NO: 769159-85-5
• Molecular Formula: C₉H₈FNO₂
• Molecular Weight: 181.1637232
• Mol File: 769159-85-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-cyclopropyl-1-fluoro-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyclopropyl-1-fluoro-2-nitrobenzene(769159-85-5)
• EPA Substance Registry System: 4-cyclopropyl-1-fluoro-2-nitrobenzene(769159-85-5)

Safety Data

• Hazardous Substances Data: 769159-85-5(Hazardous Substances Data)

Usage

General Description

4-Cyclopropyl-1-fluoro-2-nitrobenzene is a chemical compound with the molecular formula C10H9FNO2. It is characterized by the presence of a cyclopropyl group (a three-carbon ring), a fluorine atom, and a nitro group attached to a benzene ring, a six-carbon ring with alternating double and single bonds. This molecule is part of the organofluorine class of compounds, which are carbon-based compounds containing a fluorine atom, and is also a nitrobenzene, which contains a nitro group attached to a benzene ring. Its exact physical properties such as boiling point, melting point, density, and refractive index may vary and are often determined empirically. Additionally, its reactivity and other chemical behavior can be influenced by the presence and position of the functional groups in the molecule.

Upstream product

• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 411235-57-9 cyclopropylboronic acid 
• 364-75-0 1-fluoro-4-iodo-2-nitro-benzene 
• 23719-81-5 tri(cyclopropyl)indium 

Downstream Products

• 1374298-69-7 5-cyclopropyl-2-fluoroaniline 
• 769159-82-2 4-cyclopropyl-2-nitro-N-(3-(3-pyridyl)phenyl)aniline 

Relevant articles and documents

Facile synthesis of aryl(het)cyclopropane catalyzed by palladacycle

Sphos (2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′- biphenyl) adduct of cyclopalladated ferrocenylimine (IIe) exhibited highly catalytic activity for the Suzuki cross-coupling reaction of cyclopropylboronic acid with aryl(het) halides with 1 mol % catalyst loading. This process was applied to both of aryl and heteroaryl halides (Br and Cl), and made the various arylcyclopropane and heteroarylcyclopropane to be easily synthesized. A variety of substituents on the aryl halides, such as alkyl, acetyl, benzoyl, ether, formyl, carboxylate, methoxy, nitro and cyano were tolerated.

BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX

This invention relates to novel benzimidazole derivatives of formula (I), pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.