76916-12-6

Basic information

• Product Name: 4-Carbamylphencyclidine
• Synonyms: 4-Carbamylphencyclidine
• CAS NO: 76916-12-6
• Molecular Weight: 286.417
• Mol File: 76916-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Carbamylphencyclidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Carbamylphencyclidine(76916-12-6)
• EPA Substance Registry System: 4-Carbamylphencyclidine(76916-12-6)

Safety Data

• Hazardous Substances Data: 76916-12-6(Hazardous Substances Data)

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 2201-33-4 4-Bromophencyclidine 
• 3867-15-0 1-piperidinocyclohexylcarbonitrile 
• 76916-14-8 4-cyanophencyclidine 

Downstream Products

• 1747-75-7 4-(cyclohex-1-enyl)phenylamine 
• 76916-15-9 [4-(1-Piperidin-1-yl-cyclohexyl)-phenyl]-carbamic acid methyl ester 

Relevant articles and documents

Syntheses of Amine Derivatives of Phencyclidine

3-Aminophencyclidine (5) was synthesized by reduction of 3-nitrophencyclidine (3) using either H2 with Pd/C or Na2S in refluxing methanol.Attempts to isolate 4-aminophencyclidine (2), which we hoped to synthesize by hydrolysis of carbamate 15 which was isolated after reaction of amide 10 under Hofmann conditions employing bromine in CH3O(1-)/CH3OH at -40 deg C, were unsuccessful. 4-Aminomethylphencyclidine (18) was synthesized by LAH reduction of nitrile 13 as well as by reductive amination of aldehyde 20.Nitrile 13 and aldehyde 20 were synthesized from 4-bromophencyclidine (11) as was alcohol 26 which served as a precursor to 4-(2-aminoethyl)phencyclidine (19).Amine 19 was also synthesized by NaBH4 reduction of β-nitrostyrene 29 which was generated from aldehyde 20 by condensation with nitromethane using 1,5-diazabicycloundecene as the base catalyst followed by LAH reduction of resulting 4-(2-nitroethyl)phencyclidine (30).Mass spectra and 13C NMR spectra have been obtained on most of the phencyclidine derivatives.