769923-10-6

Basic information

• Product Name: 6-(2'-bromo-4'-methoxyphenoxymethyl)-1,3-dimethyl-1H-pyrimidine-2,4-dione
• CAS NO: 769923-10-6
• Molecular Weight: 355.188
• Mol File: 769923-10-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(2'-bromo-4'-methoxyphenoxymethyl)-1,3-dimethyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2'-bromo-4'-methoxyphenoxymethyl)-1,3-dimethyl-1H-pyrimidine-2,4-dione(769923-10-6)
• EPA Substance Registry System: 6-(2'-bromo-4'-methoxyphenoxymethyl)-1,3-dimethyl-1H-pyrimidine-2,4-dione(769923-10-6)

Safety Data

• Hazardous Substances Data: 769923-10-6(Hazardous Substances Data)

Upstream product

• 18592-13-7 6-chloromethyluracil 

Relevant articles and documents

Regioselective aryl radical cyclization: Access to pyrimidine-annelated Spiro heterocycles through 5-exo ring closure

Aryl radical cyclization of a range of 6-(2′- bromophenoxymethyl)-1,3-dimethyluracils 4a-g was carried out with tributyltin chloride and sodium cyanoborohydride in the presence of AIBN for four hours to give exclusively the '5-exo' cyclization products, 1,3-dimethylspiro[pyrimidine- 6,3′-2′,3′-tetrahydrobenzofuran]-2,4-diones 5a-g in 92-95% yield. The starting materials were in turn prepared in 90-92% yield by refluxing 6-chloro methyl-1,3-dimethyl uracil with various 2-bromophenols or 2-bromonaphthol in acetone in the presence of anhydrous potassium carbonate for eight hours.