7714-32-1Relevant articles and documents
Chemoselective α-sulfidation of amides using sulfoxide reagents
Leypold, Mario,D'Angelo, Kyan A.,Movassaghi, Mohammad
supporting information, p. 8802 - 8807 (2020/11/03)
The direct α-sulfidation of tertiary amides using sulfoxide reagents under electrophilic amide activation conditions is described. Employing convenient and readily available reagents, selective functionalization takes place to generate isolable sulfonium
Efficient and mild swern oxidation using a new sulfoxide and bis(trichloromethyl)carbonate
Ye, Xiaojing,Fu, Hongliang,Ma, Jiahao,Zhong, Weihui
supporting information, p. 885 - 892 (2017/01/28)
A new type of sulfoxide, 4-(2-(2-(methylsulfinyl) ethyl)-4-nitrophenyl)-morpholine (I), was designed and prepared in good yield. Upon the combination of I and bis(trichloromethyl)carbonate, the Swern oxidation of primary and secondary alcohols was significantly promoted under mild conditions, which afforded the corresponding aldehydes or ketones in good yields. It is noteworthy that the reoxidation of the isolated by-product sulfide V could be further recycled in Swern oxidation.