77227-99-7

Basic information

• Product Name: 3-Chloro-4,5-difluorobenzotrifluoride
• Synonyms: 1-chloro-2,3-difluoro-5-(trifluoromethyl)-benzen;1-chloro-2,3-difluoro-5-(trifluoromethyl)benzene;3,4-difluoro-5-chlorobenzotrifluoride;3-CHLORO-ALPHA,ALPHA,ALPHA-4,5-PENTAFLUOROTOLUENE;3-CHLORO-4,5-DIFLUOROBENZOTRIFLUORIDE;3-chloro-4,5,alpha,alpha,alpha-pentafluorotoluene;1-Chloro-2,3-difluoro-5-(trifluoromethyl)benzene, 3-Chloro-alpha,alpha,alpha,4,5-pentafluorotoluene;3-Chloro-4,5-difluorobenzotrifluoride97%
• CAS NO: 77227-99-7
• Molecular Formula: C₇H₂ClF₅
• Molecular Weight: 216.54
• EINECS: 401-930-3
• Mol File: 77227-99-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 122°C
• Flash Point: 39.9 °C
• Appearance: /
• Density: 1.51 g/cm³
• Vapor Pressure: 11.4mmHg at 25°C
• Refractive Index: 1.417
• Storage Temp.: 2-8°C
• Water Solubility: 14 mg l-1 (e)
• CAS DataBase Reference: 3-Chloro-4,5-difluorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4,5-difluorobenzotrifluoride(77227-99-7)
• EPA Substance Registry System: 3-Chloro-4,5-difluorobenzotrifluoride(77227-99-7)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-58-50-20/22-10
• Safety Statements: 26-36/37/39-61-60-51
• RIDADR: 1760
• HazardClass: IRRITANT
• Hazardous Substances Data: 77227-99-7(Hazardous Substances Data)

Usage

General Description

3-Chloro-4,5-difluorobenzotrifluoride is a chemical compound with the molecular formula C7H2ClF5. It is a colorless liquid with a molecular weight of 206.54 g/mol. 3-Chloro-4,5-difluorobenzotrifluoride is used in various industrial applications, including as a solvent, intermediate for pharmaceuticals, and as a reagent in organic synthesis. It is known to be a highly reactive and corrosive compound, and should be handled with care. It is important to follow safety measures and guidelines when working with 3-Chloro-4,5-difluorobenzotrifluoride to prevent any potential hazards.

InChI:InChI=1/C7H2ClF5/c8-4-1-3(7(11,12)13)2-5(9)6(4)10/h1-2H

Upstream product

• 50594-82-6 1-trifluoromethyl-3,4,5-trichlorobenzene 

Downstream Products

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• 142720-78-3 m-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>aniline 
• 138937-65-2 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>indolin-2-one 
• 138937-59-4 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-1-methyl-indolin-2-one 
• 142721-02-6 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-1,3-dimethylindolin-2-one 
• 142721-19-5 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-isopropylideneindolin-2-one 
• 142721-18-4 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-isopropyl-indolin-2-one 
• 142721-10-6 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-isopropylidene-1-methylindolin-2-one 
• 142720-82-9 4-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-(methylthio)-indolin-2-one 
• 138937-57-2 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-(methylthio)-indolin-2-one 
• 142720-81-8 6-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-(methylthio)-indolin-2-one 
• 142721-14-0 5-<(2-chloro-α,α,α,6-tetrafluoro-p-tolyl)oxy>-3-isopropyl-1-methylindolin-2-one 
• 1027267-34-0 [2-Amino-4-(2-chloro-6-fluoro-4-trifluoromethyl-phenoxy)-phenyl]-methylsulfanyl-acetic acid ethyl ester 
• 1028265-03-3 [2-Amino-5-(2-chloro-6-fluoro-4-trifluoromethyl-phenoxy)-phenyl]-methylsulfanyl-acetic acid ethyl ester 

Relevant articles and documents

THE FLUORINATION OF ORGANIC SUBSTRATES WITH TETRAPHENYLPHOSPHONIUM HYDROGENDIFLUORIDE

Tetraphenylphosphonium hydrogendifluoride acts as a powerful source of F- in various reactions with organic substrates to give fluorine containing products.