77278-34-3

Basic information

• Product Name: 1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-CYCLOPROPYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER;TERT-BUTYL 4-CYCLOPROPYLPIPERAZINE-1-CARBOXYLATE
• CAS NO: 77278-34-3
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.31528
• Mol File: 77278-34-3.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 296.5 °C at 760 mmHg
• Flash Point: 133.1 °C
• Appearance: /
• Density: 1.116 g/cm³
• CAS DataBase Reference: 1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(77278-34-3)
• EPA Substance Registry System: 1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(77278-34-3)

Safety Data

• Hazardous Substances Data: 77278-34-3(Hazardous Substances Data)

Usage

General Description

1-Cyclopropylpiperazine-4-carboxylic acid tert-butyl ester is a chemical compound that belongs to the class of piperazine derivatives. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-Cyclopropylpiperazine-4-carboxylic acid tert-butyl ester is known for its potential pharmacological properties, particularly in the field of drug discovery and development. It is a versatile building block that can be used in the synthesis of various bioactive molecules. Additionally, the tert-butyl ester group in the compound provides stability and protection for the carboxylic acid moiety, making it suitable for use in organic synthesis reactions. Overall, 1-Cyclopropylpiperazine-4-carboxylic acid tert-butyl ester is a valuable compound with important applications in the pharmaceutical and chemical industries.

Upstream product

• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 84098-43-1 trimethylsilyl ether of 1-methoxycyclopropanol 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 20327-23-5 1-cyclopropylpiperazine 
• 411235-57-9 cyclopropylboronic acid 

Downstream Products

• 929622-08-2 Bavisant 
• 929622-11-7 (4-cyclopropylpiperazin-1-yl)(4-((4-fluoropiperidin-1-yl)methyl)phenyl)methanone 
• 929622-21-9 4-(4-cyclopropyl-piperazine-1-carbonyl)-benzaldehyde 
• 223556-29-4 1-cyclopropylpiperazine hydrochloride 
• 20327-23-5 1-cyclopropylpiperazine 

Relevant articles and documents

AMINOPYRIMIDINE HETEROCYCLIC COMPOUND WITH ADENOSINE RECEPTOR ANTAGONISTIC ACTIVITY

Disclosed hereinis an aminopyrimidine heterocyclic compound with adenosine receptor antagonistic activity, comprising a compound of the general formula (I), or a pharmaceutically acceptable salt thereof. The aminopyrimidine heterocyclic compound with adenosine receptor antagonistic activitydisclosed herein can be used as an effective adenosine receptor antagonist, and can be used for the treatment or prevention of disorders caused by abnormal level of adenosine.

Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

Reaction of anilines, primary and secondary aliphatic amines with cyclopropylboronic acid in dichloroethane in the presence of Cu(OAc)2 (1 equiv.), 2,2′-bipyridine (1 equiv.) and sodium carbonate or sodium bicarbonate (2 equiv.) under air atmos

NOVEL COMPOUNDS

There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.