77316-78-0

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 3-(4-aminophenyl)-7-hydroxy-
• CAS NO: 77316-78-0
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.257
• Mol File: 77316-78-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 3-(4-aminophenyl)-7-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 3-(4-aminophenyl)-7-hydroxy-(77316-78-0)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 3-(4-aminophenyl)-7-hydroxy-(77316-78-0)

Safety Data

• Hazardous Substances Data: 77316-78-0(Hazardous Substances Data)

Upstream product

• 15485-80-0 7-hydroxy-3-(4-nitrophenyl)-4H-chromen-4-one 
• 104-03-0 4-nitrobenzeneacetic acid 
• 15485-63-9 1-(2,4-dihydroxyphenyl)-2-(4-nitrophenyl)ethanone 
• 108-46-3 recorcinol 

Downstream Products

• 3682-01-7 daidzein diacetate 
• 486-66-8 daidzein 

Relevant articles and documents

The synthesis and anti-inflammatory evaluation of 1,2,3-triazole linked isoflavone benzodiazepine hybrids

Copper catalyzed azide-alkyne cycloaddition was used for the first time to access a small series of eight novel 1,2,3-triazole linked isoflavone benzodiazepine hybrids. As part of this work, a previously unreported alkyne substituted pyrrolo[1,4]benzodiaz

Synthesis and biological evaluation of isoflavone amide derivatives with antihyperlipidemic and preadipocyte antiproliferative activities

A series of isoflavone amides were designed with isoflavone in place of the scaffold of 2-arylbenzoxazole as cholesterol ester transfer protein (CETP) inhibitors. Twelve new compounds were synthesized, and their inhibitory activities of CETP and preadipocyte proliferation were assayed. The hypolipidemic potency of the most effective compound HY-2c was further tested in vivo by hamster. The results indicate that HY-2c exhibited favorable antihyperlipidemic and preadipocyte antiproliferative activities.

COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH

The present invention provides novel antidipsotropic compounds. The invention further provides methods of inhibiting ALDH-2 using the compounds described herein. Methods for modulating alcohol consumption, alcohol dependence and/or alcohol abuse by administering the compounds of the invention to an individual are also provided. The present invention further provides a rationale for designing additional novel antidipsotropic compounds.