774225-33-1 Usage
Description
(Cyano-p-tolyl-methyl)-carbamic acid tert-butyl ester, with the molecular formula C12H15N3O2, is a carbamate ester derivative of carbamic acid. This chemical compound features a cyano group, a p-tolyl group, a methyl group, and a tert-butyl group. It is recognized for its stability and its role in protecting reactive functional groups during chemical reactions, making it a valuable component in organic synthesis and medicinal chemistry.
Uses
Used in Organic Synthesis:
(Cyano-p-tolyl-methyl)-carbamic acid tert-butyl ester is used as a reagent in organic synthesis for its ability to protect reactive functional groups, facilitating the creation of complex molecular structures with greater ease and precision.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (Cyano-p-tolyl-methyl)-carbamic acid tert-butyl ester serves as a versatile building block. It is utilized in the synthesis of various drugs and bioactive compounds, contributing to the development of novel pharmaceuticals with potential therapeutic applications.
Used in Pharmaceutical Applications:
(Cyano-p-tolyl-methyl)-carbamic acid tert-butyl ester has been studied for its potential pharmaceutical applications, indicating its value in the development of new medications and therapies to address various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 774225-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,4,2,2 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 774225-33:
(8*7)+(7*7)+(6*4)+(5*2)+(4*2)+(3*5)+(2*3)+(1*3)=171
171 % 10 = 1
So 774225-33-1 is a valid CAS Registry Number.
774225-33-1Relevant articles and documents
Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure
Yan, Shunqi,Larson, Gary,Wu, Jim Z.,Appleby, Todd,Ding, Yili,Hamatake, Robert,Hong, Zhi,Yao, Nanhua
, p. 63 - 67 (2007/10/03)
Structure-activity relationships (SAR) of 1 against HCV NS5B polymerase were described. SAR explorations and further structure-based design led to the identifications of 2 and 3 as novel HCV NS5B inhibitors. X-ray structure of 3 in complex with NS5B polymerase was obtained at a resolution of 2.2 A, and confirmed the design.
