779206-51-8

Basic information

• Product Name: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester
• Synonyms: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester
• CAS NO: 779206-51-8
• Molecular Weight: 206.241
• Mol File: 779206-51-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 286.6±33.0 °C(Predicted)
• Density: 1.162±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester(779206-51-8)
• EPA Substance Registry System: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester(779206-51-8)

Safety Data

• Hazardous Substances Data: 779206-51-8(Hazardous Substances Data)

Usage

Functional groups

Ester, cyclopropane ring, phenyl group, and methoxy group

Structure

Contains a cyclopropane ring fused to a phenyl group, with a methoxy group substituting the phenyl group

Applications

Organic synthesis, pharmaceutical research, and development of new drugs and bioactive compounds

Chemical properties

Unique reactivity due to the presence of a cyclopropane ring and a phenyl group

Biological properties

Potential for therapeutic applications and biological activities

Research potential

Further exploration of its reactivity and biological activities may lead to the discovery of novel drugs and compounds with therapeutic potential

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 104-47-2 p-methoxybenzylnitrile 
• 16728-00-0 1-(4-methoxyphenyl)cyclopropane-1-carbonitrile 
• 16728-01-1 1-(4-methoxyphenyl)-1-cyclopropanecarboxylic acid 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 67-56-1 methanol 

Downstream Products

• 1006875-72-4 1-(4-methoxyphenyl)cyclopropanecarbohydrazide 
• 952664-63-0 (E)-methyl 1-(3-(1-(acetoxyimino)ethyl)-4-hydroxyphenyl)cyclopropanecarboxylate 
• 936727-45-6 1-(2,3-dihydrobenzofuran-5-yl)cyclopropanecarboxylic acid 
• 16728-03-3 1-(4-Methoxyphenyl)cyclopropyl-1-carbinol 
• 952664-61-8 1-(3-acetyl-4-hydroxyphenyl)cyclopropanecarboxylic methyl ester 
• 952664-59-4 1-[4-(2-carboxyethoxy)phenyl]cyclopropanecarboxylic acid methyl ester 
• 952664-58-3 1-[4-(2-tert-butoxycarbonyl-ethoxy)phenyl]cyclopropanecarboxylic acid methyl ester 
• 936727-37-6 1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester 
• 936727-36-5 1-(3-hydroxymethyl-4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester 
• 936727-35-4 1-(3-chloromethyl-4-methoxyphenyl)-cyclopropanecarboxylic acid methyl ester 
• 936727-40-1 1-[3,5-diiodo-4-(2-methyl-allyloxy)phenyl]cyclopropanecarboxylic acid methyl ester 
• 936727-39-8 1-(4-hydroxy-3,5-diiodophenyl)cyclopropanecarboxylic acid methyl ester 

Relevant articles and documents

Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use

The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Modulators of ATP-binding cassette transporters

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.