77985-10-5

Basic information

• Product Name: 2-[4-(4-Chloro-benzyl)-phenoxy]-2-methyl-butyric acid 2-acetylamino-ethyl ester
• Synonyms: 2-[4-(4-Chloro-benzyl)-phenoxy]-2-methyl-butyric acid 2-acetylamino-ethyl ester
• CAS NO: 77985-10-5
• Molecular Weight: 403.906
• Mol File: 77985-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(4-Chloro-benzyl)-phenoxy]-2-methyl-butyric acid 2-acetylamino-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(4-Chloro-benzyl)-phenoxy]-2-methyl-butyric acid 2-acetylamino-ethyl ester(77985-10-5)
• EPA Substance Registry System: 2-[4-(4-Chloro-benzyl)-phenoxy]-2-methyl-butyric acid 2-acetylamino-ethyl ester(77985-10-5)

Safety Data

• Hazardous Substances Data: 77985-10-5(Hazardous Substances Data)

Upstream product

• 52890-73-0 4-(4-chloro-benzyl)-phenol 
• 55937-99-0 beclobrate 
• 5398-71-0 2-bromo-2-ethyl-2-methyl acetic acid ethyl ester 
• 142-26-7 2-acetylaminoethanol 
• 71548-88-4 Beclobric acid 

Relevant articles and documents

Beclobrate and eniclobrate hydrochloride, new diphenylmethane derivatives as agents for lowering cholesterol and triglyceride levels. Part I: Synthesis and consideration of structure-activity relationships (author's transl)

Within the course of a research project for finding new lipid-lowering substances with better therapeutic indices than the standard agent in use, various diphenylmethane derivatives were synthesized and tested with respect to their activity and toxicity. On the basis of these results Sgd 24774 (beclobrate) and Sgd 33374 (eniclobrate-hydrochloride) were selected for further investigation and clinical studies.