77989-56-1 Usage
Description
[1,1'-Biphenyl]-2-amine, N-ethyl-, also known as N-ethyl-[1,1'-biphenyl]-2-amine, is a chemical compound with the molecular formula C14H15N. It is an amine derivative of biphenyl, which is a compound consisting of two benzene rings linked together. The addition of an ethyl group to the amine group of [1,1'-Biphenyl]-2-amine results in N-ethyl-[1,1'-Biphenyl]-2-amine. [1,1'-Biphenyl]-2-amine, N-ethylis characterized by its unique chemical structure and properties, making it a versatile building block in various applications.
Uses
Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-2-amine, N-ethylis used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows it to be a key component in the development of new drugs and medications, potentially contributing to advancements in healthcare and medicine.
Used in Research and Laboratory Settings:
In research and laboratory settings, [1,1'-Biphenyl]-2-amine, N-ethylserves as a reagent or intermediate in chemical reactions. Its distinct properties make it a valuable tool for scientists and researchers working on the development of new chemical compounds and materials.
Used in Organic Electronics and Materials Science:
Due to its unique chemical structure and properties, [1,1'-Biphenyl]-2-amine, N-ethylhas potential applications in the field of organic electronics and materials science. It may be utilized in the development of new materials with specific electronic properties, contributing to the advancement of technology and innovation in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 77989-56-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,8 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 77989-56:
(7*7)+(6*7)+(5*9)+(4*8)+(3*9)+(2*5)+(1*6)=211
211 % 10 = 1
So 77989-56-1 is a valid CAS Registry Number.
77989-56-1Relevant articles and documents
Selective N-alkylation of amines using nitriles under hydrogenation conditions: Facile synthesis of secondary and tertiary amines
Ikawa, Takashi,Fujita, Yuki,Mizusaki, Tomoteru,Betsuin, Sae,Takamatsu, Haruki,Maegawa, Tomohiro,Monguchi, Yasunari,Sajiki, Hironao
supporting information; experimental part, p. 293 - 304 (2012/02/01)
Nitriles were found to be highly effective alkylating reagents for the selective N-alkylation of amines under catalytic hydrogenation conditions. For the aromatic primary amines, the corresponding secondary amines were selectively obtained under Pd/C-catalyzed hydrogenation conditions. Although the use of electron poor aromatic amines or bulky nitriles showed a lower reactivity toward the reductive alkylation, the addition of NH4OAc enhanced the reactivity to give secondary aromatic amines in good to excellent yields. Under the same reaction conditions, aromatic nitro compounds instead of the aromatic primary amines could be directly transformed into secondary amines via a domino reaction involving the one-pot hydrogenation of the nitro group and the reductive alkylation of the amines. While aliphatic amines were effectively converted to the corresponding tertiary amines under Pd/C-catalyzed conditions, Rh/C was a highly effective catalyst for the N-monoalkylation of aliphatic primary amines without over-alkylation to the tertiary amines. Furthermore, the combination of the Rh/C-catalyzed N-monoalkylation of the aliphatic primary amines and additional Pd/C-catalyzed alkylation of the resulting secondary aliphatic amines could selectively prepare aliphatic tertiary amines possessing three different alkyl groups. According to the mechanistic studies, it seems reasonable to conclude that nitriles were reduced to aldimines before the nucleophilic attack of the amine during the first step of the reaction.
