78071-30-4

Basic information

• Product Name: 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID
• Synonyms: 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID;4-methyl-3-Thiophenecarboxylic acid
• CAS NO: 78071-30-4
• Molecular Formula: C₆H₆O₂S
• Molecular Weight: 142.18
• Mol File: 78071-30-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 136-138 ºC
• Boiling Point: 274 ºC
• Flash Point: 119 ºC
• Appearance: /
• Density: 1.319
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: 2-8°C(protect from light)
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 4.18±0.20(Predicted)
• CAS DataBase Reference: 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID(78071-30-4)
• EPA Substance Registry System: 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID(78071-30-4)

Safety Data

• Hazardous Substances Data: 78071-30-4(Hazardous Substances Data)

Usage

General Description

4-Methylthiophene-3-carboxylic acid is a chemical compound with the molecular formula C7H6OS. It is a derivative of thiophene, a five-membered heterocyclic compound that contains sulfur. The presence of a carboxylic acid group in its structure makes it an organic acid. 4-Methylthiophene-3-carboxylic acid is commonly utilized in the pharmaceutical and agrochemical industries as a building block for the synthesis of various drugs and pesticides. It is also used in the production of flavors and fragrances. Additionally, 4-Methylthiophene-3-carboxylic acid plays a role as an intermediate in the synthesis of other organic compounds. Overall, this chemical has significant importance in the field of organic chemistry and has various industrial applications.

InChI:InChI=1/C6H6O2S/c1-4-2-9-3-5(4)6(7)8/h2-3H,1H3,(H,7,8)

Upstream product

• 16494-41-0 3-iodo-4-methylthiophene 
• 30318-99-1 3-bromo-4-methylthiophene 
• 124-38-9 carbon dioxide 
• 43088-42-2 2-amino-4-methyl-thiophene-3-carboxylic acid ethyl ester 
• 73229-39-7 4-methylthiophene-3-carbonitrile 

Downstream Products

• 63826-85-7 (2,4-dimethylthiophen-3-yl)methanol 
• 503308-96-1 2,4-dimethylthiophene-3-carboxylic acid 

Relevant articles and documents

PYRAZOLE AMIDE DERIVATIVE

The present invention relates to a novel compound having a function of inhibiting RORγ activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Lignan analogues, methods of preparation thereof and anti-hyperlipemic agents

An anti-hyperlipemic agent which has a potent activity of reducing LDL and VLDL cholesterols, which are thought to be a risk factor for arteriosclerosis among total blood cholesterols, and which is excellent in the antioxidant activity on LDL, is provided. Additionally, a compound and a pharmaceutically acceptable salt thereof are disclosed, which is represented by Formula (I): STR1 [wherein R1 is a power alkyl, cycloalkyl, cycloalkyl-lower alkyl, aryl or aralkyl group which is optionally substituted; R2 is a group represented by the formula: --COOR' (wherein R' is a lower alkyl or aralkyl which is optionally substituted), lower alkyl or halogenated lower alkyl; or R1 and R2, together with adjacent carbonyl group, form a cyclohexanone ring represented by the formula: STR2 R3 is a phenyl group optionally being substituted, and, ring A is a benzene nucleus which is optionally substituted, or a heterocyclic ring containing S or O optionally being substituted].