781613-23-8 Usage
Description
XL-647 is a potent and selective EGFR phosphorylation inhibitor, characterized by its ability to target and inhibit the phosphorylation of the epidermal growth factor receptor. This orally available, multi-target tyrosine kinase inhibitor has garnered attention for its potential therapeutic applications in cancer treatment.
Uses
Used in Oncology:
XL-647 is used as an anticancer agent for patients suffering from lung cancer. Its selectivity for EGFR phosphorylation makes it a promising candidate for targeted cancer therapy, potentially leading to improved treatment outcomes and reduced side effects compared to traditional chemotherapy.
Used in Pharmaceutical Development:
As a multi-target tyrosine kinase inhibitor, XL-647 is utilized in the development of novel pharmaceuticals aimed at treating various cancers driven by aberrant EGFR signaling. Its oral availability and selectivity for EGFR phosphorylation make it a valuable asset in the creation of targeted therapies with the potential for better patient compliance and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 781613-23-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,1,6,1 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 781613-23:
(8*7)+(7*8)+(6*1)+(5*6)+(4*1)+(3*3)+(2*2)+(1*3)=168
168 % 10 = 8
So 781613-23-8 is a valid CAS Registry Number.
InChI:InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13?,14-,15+
