78510-02-8

Basic information

• Product Name: 1-OCTANOL-1,1-D2
• Synonyms: 1-OCTANOL-1,1-D2;N-OCTYL-1,1-D2 ALCOHOL
• CAS NO: 78510-02-8
• Molecular Formula: C₈H₁₈O
• Molecular Weight: 132.24
• Mol File: 78510-02-8.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-OCTANOL-1,1-D2(CAS DataBase Reference)
• NIST Chemistry Reference: 1-OCTANOL-1,1-D2(78510-02-8)
• EPA Substance Registry System: 1-OCTANOL-1,1-D2(78510-02-8)

Safety Data

• Hazardous Substances Data: 78510-02-8(Hazardous Substances Data)

Usage

Uses

n-Octyl-1,1-d2 Alcohol (CAS# 78510-02-8) is a useful isotopically labeled research compound.

Upstream product

• 758-12-3 deuteroacetic acid 
• 106-32-1 octanoic acid ethyl ester 
• 1118-92-9 N,N-dimethyloctamide 
• 111-64-8 n-octanoic acid chloride 
• 111-11-5 methyl octanate 
• 124-07-2 Octanoic acid 

Downstream Products

• 146801-59-4 (1S)-1-(p-tolylsulfonyloxy)-[1-⁽²⁾H₁]-octane 
• 86412-09-1 4,4'-bis-(<1,1-(2)H2>octyloxy)azoxybenzene 
• 111-65-9 octane 
• 936716-87-9 C₂₈H₃₂O₃ 
• 1337934-89-0 C₂₈H₃₁⁽²⁾HO₃ 
• 89232-08-6 1-iodo-[1,1-D₂]octane 
• 54439-94-0 1,1-d₂-oct-1-ene 
• 111-66-0 oct-1-ene 
• 13389-42-9 trans-2-Octene 
• 14919-01-8 (E)-3-octene 
• 629-27-6 1-Iodooctane 
• 86423-34-9 <1,1-(2)H2>octyl bromide 

Relevant articles and documents

Equilibration of 1-Octanol with Alcohol Dehydrogenase. Evidence for Horse Liver Alcohol Dehydrogenase Responsibility for Exchange of the 1-pro-S Hydrogen Atom

Equilibration of hydrogen atoms of 1-octanol with water, mediated by the system horse liver alcohol dehydrogenase-NAD/NADH-diaphorase, involves a rapid exchange of 1-pro-R hydrogen atoms and a slow exchange of 1-pro-S hydrogen atoms.Yeast alcohol dehydrogenase has an apparent absolute stereospecificity for the 1-pro-R hydrogen atom of 1-octanol; replacement of horse liver dehydrogenase by yeast alcohol dehydrogenase in the above system results in exchange of only the 1-pro-R hydrogen atom of 1-octanol.In the absence of horse liver or yeast alcohol dehydrogenase, no exchange of C-1 hydrogen atoms of 1-octanol occurs.Thus, horse liver alcohol dehydrogenase is directly responsible for promoting exchange of the 1-pro-S hydrogen atom of 1-octanol with water hydrogen atoms.

Method used for reduction of tertiary amide into alcohols and/or amines

The invention discloses a method used for reduction of tertiary amide into alcohols and/or amines. The method comprises following steps: tertiary amide, an alkali metal reagent, and a proton donor agent are added into an organic solvent for a following reaction selectively: when the proton donor agent is a raw material alcohol and/or inorganic salt aqueous solution, the reaction product is an alcohol compound and/or tertiary amine compound. The method is capable of realizing selective reduction of tertiary amide into alcohols and tertiary amine compounds, the yield is high, the suitable rangeis wide, operation is safe and simple, the adopted raw materials are cheap and easily available; no precious metal catalyst, toxic silanes, and flammable and combustible metal hydrides are adopted; notoxic by product is generated; reaction is more friendly to the environment; problems in the prior art that amide compound reducing method operation is complex, conditions are strict, and control ofproducts is difficult are solved.

Site-specific 2H-labeled oleic acid and derived esters for use as tracers of ethyl oleate metabolism in honey bees

The inventory of labeled fatty acids and protocols for their syntheses are constantly increasing, but site-specific labeled precursors in biosynthetic studies are still needed. Ethyl oleate (EO) is an important primer pheromone in honeybees, which is responsible for the regulation of behavioral maturation. During our biosynthetic studies on EO, a site-specific labeled oleic acid precursor was required. In this report, a synthetic route adaptable to the preparation of [9,10,11,11-D4] oleic acid and its derived esters for use as tracers of EO metabolism in honey bees is presented. Copyright