78539-94-3

Basic information

• Product Name: 3-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine
• Synonyms: 3-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine
• CAS NO: 78539-94-3
• Molecular Weight: 229.669
• Mol File: 78539-94-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine(78539-94-3)
• EPA Substance Registry System: 3-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine(78539-94-3)

Safety Data

• Hazardous Substances Data: 78539-94-3(Hazardous Substances Data)

Upstream product

• 6238-67-1 α-(2-chlorophenyl)-2-pyridylmethanol 
• 89-98-5 2-chloro-benzaldehyde 
• 98-98-6 2-Picolinic acid 
• 78539-97-6 2-[(2-chlorophenyl)(hydrazono)methyl]pyridine 
• 1694-57-1 (2-chlorophenyl)(pyridin-2-yl)methanone 

Relevant articles and documents

Facile one-pot synthesis of [1,2,3]triazolo[1,5-a]pyridines from 2-acylpyridines by copper(II)-catalyzed oxidative N-N bond formation

An efficient and simple method for the synthesis of various [1,2,3]triazolo[1,5-a]pyridines has been established. The method involves a copper(II)-catalyzed oxidative N-N bond formation that uses atmospheric oxygen as the terminal oxidant following hydrazonation in one pot. The use of ethyl acetate as the solvent dramatically promotes the oxidative N-N bond-formation reaction and enables the application of oxidative cyclization in the efficient one-pot reaction. A mechanism for the reaction was proposed on the basis of the results of a spectroscopic study. In the same pot: [1,2,3]Triazolo[1,5-a] pyridines are synthesized from the corresponding 2-acylpyridines by a one-pot method, consisting of hydrazonation followed by oxidative cyclization through copper(II)-catalyzed N-N bond formation (see scheme).