787544-61-0

Basic information

• Product Name: (R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID
• Synonyms: RARECHEM DF HC P253;(R)-BETA-(3-NITROPHENYL)ALANINE;(R)-3-AMINO-3-(3-NITROPHENYL)PROPANOIC ACID;(R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID;L-BETA-HOMO(3-NITROPHENYL)GLYCINE;H-PHG(3-NO2)-(C*CH2)OH;H-D-BETA-PHE(3-NO2)-OH;(R)-3-(3-NITROPHENYL)-BETA-ALANINE
• CAS NO: 787544-61-0
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.19
• EINECS: 200-528-9
• Product Categories: 3-Amino-3-phenylpropanoic Acid Analogs;API intermediates;B-Amino
• Mol File: 787544-61-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 384.5 °C at 760 mmHg
• Flash Point: 186.4 °C
• Appearance: /
• Density: 1.404 g/cm³
• Vapor Pressure: 1.34E-06mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: (R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID(787544-61-0)
• EPA Substance Registry System: (R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID(787544-61-0)

Safety Data

• Hazardous Substances Data: 787544-61-0(Hazardous Substances Data)

Usage

General Description

(R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID is a chemical compound with the molecular formula C9H10N2O4. It is a derivative of propionic acid and contains an amino group and a nitro group on the phenyl ring. (R)-3-AMINO-3-(3-NITRO-PHENYL)-PROPIONIC ACID has potential applications in pharmaceuticals, as it may exhibit biological activity or be used as a building block for the synthesis of other compounds. Its specific properties, uses, and potential hazards would depend on the context and the specific application for which it is intended.

InChI:InChI=1/C9H10N2O4/c10-8(5-9(12)13)6-2-1-3-7(4-6)11(14)15/h1-4,8H,5,10H2,(H,12,13)/t8-/m1/s1

Upstream product

• 5678-47-7 3-amino-3-(3-nitro-phenyl)-propionic acid 

Downstream Products

• 918810-80-7 (R)-ethyl 3-(3-aminophenyl)-3-(tert-butoxycarbonylamino)propanoate 
• 499995-72-1 (R)-3-amino-3-(3-nitrophenyl)propanoic acid hydrochloride 

Relevant articles and documents

Kinetic Resolution of Aromatic β-Amino Acids Using a Combination of Phenylalanine Ammonia Lyase and Aminomutase Biocatalysts

An enzymatic strategy for the preparation of (R)-β-arylalanines employing phenylalanine aminomutase and ammonia lyase (PAM and PAL) enzymes has been demonstrated. Candidate PAMs with the desired (S)-selectivity from Streptomyces maritimus (EncP) and Bacillus sp. (PabH) were identified via sequence analysis using a well-studied template sequence. The newly discovered PabH could be linked to the first ever proposed biosynthesis of pyloricidin-like secondary metabolites and was shown to display better β-lyase activity in many cases. In spite of this, a method combining the higher conversion of EncP with a strict α-lyase from Anabaena variabilis (AvPAL) was found to be more amenable, allowing kinetic resolution of five racemic substrates and a preparative-scale reaction with >98% (R) enantiomeric excess. This work represents an improved and enantiocomplementary method to existing biocatalytic strategies, allowing simple product separation and modular telescopic combination with a preceding chemical step using an achiral aldehyde as starting material. (Figure presented.).