78957-20-7

Basic information

• Product Name: 3-(HYDROXYMETHYL)PHENYL ACETATE
• Synonyms: 3-(HYDROXYMETHYL)PHENYL ACETATE
• CAS NO: 78957-20-7
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 0
• Mol File: 78957-20-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(HYDROXYMETHYL)PHENYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(HYDROXYMETHYL)PHENYL ACETATE(78957-20-7)
• EPA Substance Registry System: 3-(HYDROXYMETHYL)PHENYL ACETATE(78957-20-7)

Safety Data

• Hazardous Substances Data: 78957-20-7(Hazardous Substances Data)

Upstream product

• 34231-78-2 3-formylphenyl acetate 
• 108-05-4 vinyl acetate 
• 620-24-6 3-Hydroxybenzyl alcohol 
• 60-29-7 diethyl ether 
• 100-83-4 meta-hydroxybenzaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 1118974-23-4 3-acetyloxybenzyl diethylphosphate 
• 299217-26-8 C₄₈H₅₆N₄O₁₀ 
• 299217-27-9 C₄₆H₅₄N₄O₉ 
• 299217-24-6 8-[3'-(i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1-(3'''-acetoxybenzyl)]-quinolinone 
• 299217-25-7 8-[3'-(i-pentyloxy)-5'-(3''-aminobenzyloxy)benzyloxy]-2-[1-(3'''-acetoxybenzyl)]-quinolinone 
• 661466-52-0 12β-dihydroartemisinyl m-hydroxybenzyl ether 
• 4530-44-3 3-acetoxybenzyl chloride 
• 49617-80-3 m-(bromomethyl)phenyl acetate 

Relevant articles and documents

MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF

Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.

ANTIBACTERIAL AGENTS

Compounds of formula (I) have antibacterial activity wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is =C(R1)- or =N-; R1 is hydrogen or an optional substituent and R2 is hydrogen, methyl, or fluorine; or R1 and R2 taken together are -CH2-, -CH2CH2-, -O-, or, in either orientation, -O- CH2- Or -OCH2CH2-; R3 is a radical of formula -(Alk1)m-(Z)p-(Alk2)n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z is -O-, -S-, -S(O)-, -S(O2)-, -NH-, -N(CH3)-, -N(CH2CH3)-, -C(=O)-, -O-(C=O)-, -C(=O)-O-, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted divalent bicyclic heterocyclic radical having 5 to 10 ring atoms; Alk1 and Alk2 are optionally substituted C1C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radicals, which may optionally terminate with or be interrupted by -O-, -S-, -S(O)-, -S(O2)-, -NH-, -N(CH3)-, or -N(CH2CH3)-; and Q is hydrogen, halogen, nitrile, or hydroxyl or an optionally substituted monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted bicyclic heterocyclic radical having 5 to 10 ring atoms.

Dendroid peptide structural mimetics of ω-conotoxin MVIIA based on a 2(1H)-quinolinone core

Three mimetics of the peptide ω-Conotoxin MVIIA have been synthesised following the dendroid approach. The three key central amino acids of the natural peptide are mimicked by phenylguanidine (arginine), isopentyl (leucine) and aryl alcohol (tyrosine) att