78964-11-1

Basic information

• Product Name: (S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid
• Synonyms: 1-Benzyl-5-oxopyrrolidine-2-carboxylic acid
• CAS NO: 78964-11-1
• Molecular Formula: C₁₂H₁₃NO₃
• Molecular Weight: 219.23652
• Mol File: 78964-11-1.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid(78964-11-1)
• EPA Substance Registry System: (S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid(78964-11-1)

Safety Data

• Hazardous Substances Data: 78964-11-1(Hazardous Substances Data)

Usage

General Description

(S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid is a chemical compound classified as a pyrrolidine carboxylic acid derivative. It is also known by its systematic IUPAC name, (S)-1-benzyl-5-oxo-2-pyrrolidinecarboxylic acid. (S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid has a molecular formula of C14H15NO3 and a molecular weight of 245.27 g/mol. It is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological properties and biological activities. It may also have applications in the development of new drugs and medical treatments. Additional research may be warranted to further explore the potential uses and effects of this chemical compound.

Upstream product

• 103301-78-6 1-benzyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 79-19-6 thiosemicarbazide 
• 100-52-7 benzaldehyde 
• 77539-18-5 (S)-(+)-2-benzylamino glutaric acid 
• 103301-78-6 methyl (2S)-1-benzyl-5-pyrrolidone-2-carboxylate 
• 90741-27-8 (S)-tert-butyl 1-benzyl-5-oxopyrrolidine-2-carboxylate 
• 56-86-0 L-glutamic acid 
• 100-39-0 benzyl bromide 
• 98-79-3 L-Pyroglutamic acid 
• 4931-66-2 methyl (S)-pyroglutamate 
• 35418-16-7 L-t-butyl pyroglutamate 
• 100-44-7 benzyl chloride 
• 4931-66-2 methyl 5-oxopyrrolidine-2-carboxylate 
• 149-87-1 Pyroglutamic acid 

Downstream Products

• 103301-78-6 methyl (2S)-1-benzyl-5-pyrrolidone-2-carboxylate 
• 378238-39-2 9-(N-benzyl-(S)-pyroglutamyl)-β-carboline 
• 1001389-15-6 N-[(2-chloro-4-fluorophenyl)methyl]-5-oxo-1-(phenylmethyl)-prolinamide 
• 329273-63-4 (S)-3-(4-Amino-phenyl)-2-[((S)-1-benzyl-5-oxo-pyrrolidine-2-carbonyl)-amino]-propionic acid benzyl ester 

Relevant articles and documents

Substituted 5-oxo-pyrrolidine derivative, and preparation method and applications thereof

The invention belongs to the technical field of medicine, relates to a substituted 5-oxo-pyrrolidine derivative disclosed in generation formula I, and a preparation method and applications thereof, and more specifically relates to applications of the substituted 5-oxo-pyrrolidine derivative in preparation of anti-cerebral ischemia medicines as a nerve protective agent, and a pharmaceutical composition taking the substituted 5-oxo-pyrrolidine derivative and a pharmaceutically acceptable salt of the substituted 5-oxo-pyrrolidine derivative as active components. The pharmaceutical composition contains the substituted 5-oxo-pyrrolidine derivative and a pharmaceutical excipient and/or a diluent of the substituted 5-oxo-pyrrolidine derivative. In the general formula I, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, Y, and n are defined in the patent specification and patent claims.

A the non-peptide class perishes weakly inhibiting protein antagonists and its synthetic method and application (by machine translation)

This invention discloses a kind of the non-peptide class perishes weakly inhibiting protein antagonist and method for preparing the same and application, which aims to provide a better anticancer effect with the non-peptide class perishes weakly inhibitin

An efficient and straight forward strategy for the synthesis of enantiomerically pure (S)-1-benzyl-5-(alkyl/aryl amino) methyl-pyrrolidin-2-ones

A simple, efficient and straightforward strategy for the synthesis of enantiomerically pure (S)-5-((alkyl/aryl amino) methyl)-pyrrolidin-2-ones from N-benzyl-5(S)-pyroglutaminol through Mitsunobu reaction has been described. These pyrrolidin-2-ones have great potential to act as asymmetric precursors for the synthesis of bioactive compounds/ natural products requiring suitably substituted aminomethyl group at C-5 of native pyrrolidin-2-ones.