79127-35-8

Basic information

• Product Name: echinosporin
• Synonyms: echinosporin;(1S)-1β,4aβ,5,7aβ-Tetrahydro-5β-hydroxy-8-oxo-1α,5α-(epoxymethano)cyclopenta[c]pyran-3-carboxamide;Antibiotic XK 213;Echinosporin (Streptomyces);NSC 357683;XK 213
• CAS NO: 79127-35-8
• Molecular Formula: C10H9NO5
• Molecular Weight: 223.183
• Mol File: 79127-35-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 635.1°C at 760 mmHg
• Flash Point: 337.9°C
• Appearance: /
• Density: 1.709g/cm³
• Vapor Pressure: 8.4E-19mmHg at 25°C
• Refractive Index: 1.687
• PKA: 10.92±0.40(Predicted)
• CAS DataBase Reference: echinosporin(CAS DataBase Reference)
• NIST Chemistry Reference: echinosporin(79127-35-8)
• EPA Substance Registry System: echinosporin(79127-35-8)

Safety Data

• Hazardous Substances Data: 79127-35-8(Hazardous Substances Data)

Usage

Uses

Echinosporin is an apoptotic cell-cycle inhibitor.

InChI:InChI=1/C10H9NO5/c11-7(12)6-3-5-4-1-2-10(5,14)9(13)16-8(4)15-6/h1-5,8,14H,(H2,11,12)/t4-,5+,8+,10+/m1/s1

Upstream product

• 123487-81-0 (1S,4aS,5S,7aS)-3-Carbamoyl-1,5-dihydroxy-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-5-carboxylic acid 
• 123487-75-2 (3R,3aR,3bR,4S,6aS,6bR)-2,3,4-Trihydroxy-3,3a,3b,4,6a,6b-hexahydro-2H-1-oxa-cyclobutadicyclopentene-4-carboxylic acid methyl ester 
• 123487-76-3 (3R,3aR,3bR,4S,6aS,6bR)-3,4-Dihydroxy-2-oxo-3,3a,3b,4,6a,6b-hexahydro-2H-1-oxa-cyclobutadicyclopentene-4-carboxylic acid methyl ester 
• 123487-73-0 C₁₄H₁₈O₅ 
• 123487-78-5 (1R,2S,5S,6R,7S)-7-(Carbamoyl-hydroxy-methyl)-2,6-dihydroxy-bicyclo[3.2.0]hept-3-ene-2-carboxylic acid methyl ester 
• 123538-47-6 (1S,4aS,5S,7aS)-3-Carbamoyl-1,5-dihydroxy-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-5-carboxylic acid methyl ester 
• 123487-72-9 C₁₃H₁₅F₃O₆S 
• 123487-74-1 C₁₄H₁₈O₆ 
• 123487-81-0 (4aS,5S,7aS)-3-Carbamoyl-1,5-dihydroxy-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-5-carboxylic acid 
• 123487-70-7 C₁₂H₁₆O₄ 

Downstream Products

• 114825-57-9 (1S,4S,7S,8S)-4-Hydroxy-10-phenylaminomethyl-2,11-dioxa-tricyclo[5.4.0.0^4,8]undeca-5,9-dien-3-one 

Relevant articles and documents

Applications of an asymmetric [2 + 2]-photocycloaddition. Total synthesis of (-)-echinosporin. Construction of an advanced 11-deoxyprostaglandin intermediate

The first total synthesis of the novel antitumor metabolite (-)-echinosporin (1) has been achieved. Asymmetric [2 + 2]-photocycloaddition of dihydrofuran acetonide (+)-8 to 2-cyclopentenone (7) constituted the cornerstone of the synthetic strategy. Mitsun