792898-30-7

Basic information

• Product Name: 3-Isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-6,7-dihydroxy-,(3R)-(9CI)
• Synonyms: 3-Isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-6,7-dihydroxy-,(3R)-(9CI)
• CAS NO: 792898-30-7
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.2
• Product Categories: ALCOHOL
• Mol File: 792898-30-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-6,7-dihydroxy-,(3R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-6,7-dihydroxy-,(3R)-(9CI)(792898-30-7)
• EPA Substance Registry System: 3-Isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-6,7-dihydroxy-,(3R)-(9CI)(792898-30-7)

Safety Data

• Hazardous Substances Data: 792898-30-7(Hazardous Substances Data)

Usage

Family

Isoquinoline carboxylic acid

Derivative of

Isoquinoline

Contains

Carboxyl group

Chirality

Chiral molecule with a specific three-dimensional arrangement of atoms

Appearance

White to off-white solid

Chemical properties

Useful in various applications, including in the pharmaceutical industry as a potential drug candidate
Further research and studies are warranted to explore its potential uses and properties.

Upstream product

• 50-00-0 formaldehyd 
• 63-84-3 dopa 
• 59-92-7 levodopa 

Downstream Products

• 611239-26-0 (S)-methyl 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate 

Relevant articles and documents

CONVERSION OF DOPA TO TETRAHYDROISOQUINOLINES AND STIZOLOBIC ACID IN A CALLUS CULTURE OF STIZOLOBIUM HASSJOO

Isolation and identification of L-3-carboxy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and L-1-methyl 3-carboxy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline from seeds and callus of S. hassjoo are described.Administration of -labelled DOPA to a callus culture of this legume resulted in the incorporation of radioactivity into L-3-carboxy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, L-1-methyl-3-carboxy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and stizolobic acid, which was confirmed by constant specific radioactivity after co-crystallization with authentic samples of each compound. - Key Word Index - Stizolobium hassjoo; Leguminosae; Yokohama velvet bean; tetrahydroisoquinolines; stizolobic acid; DOPA; callus culture.

Preparation of chiral 1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid and derivatives

The present invention relates to a process for the production of (S)-1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid compounds (1) and their derivatives from Levodopa (L-Dopa). The ultimately prepared compounds are used as intermediates for, but not limited to, the preparation of substituted derivatives of 1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid wherein R1is hydrogen, lower alkyl, C2-C12 acyl, or R1O together are methylenedioxy; R2is hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, aryl, substituted aryl, aralkyl or substituted aralkyl group; and R3is hydrogen, C2-C12 acyl group, benzyl, alkoxylcarbonyl group, or aralkoxyl carbonyl group.

A new efficient synthetic process for the construction of the pentacyclic core of marine alkaloid ecteinascidins

The pentacyclic core of ecteinascidins was constructed from two fundamental building blocks, the 1,2,3,4-tetrahydroisoquinoline derivative and the substituted phenylalanine derivative, via 8 steps using readily available L-Dopa as starting material. The k