79370-15-3Relevant articles and documents
Amide isosteres in structure-activity studies of antibacterial minor groove binders
Khalaf, Abedawn I.,Anthony, Nahoum,Breen, David,Donoghue, Gavin,MacKay, Simon P.,Scott, Fraser J.,Suckling, Colin J.
experimental part, p. 5343 - 5355 (2012/01/06)
Antibacterial minor groove binders related to the natural product, distamycin, are development candidates for novel antibiotics. Alkenes have been found to be effective substitutes for the isosteric amide links in some positions and alkyl groups larger th