79521-18-9

Basic information

• Product Name: 5,5'-[2-(1-hydroxypropyl)-1,4-phenylenebis(oxy)]bis[2,2-dimethylpentanoic acid]
• Synonyms: 5,5'-[2-(1-hydroxypropyl)-1,4-phenylenebis(oxy)]bis[2,2-dimethylpentanoic acid]
• CAS NO: 79521-18-9
• Molecular Weight: 424.535
• Mol File: 79521-18-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,5'-[2-(1-hydroxypropyl)-1,4-phenylenebis(oxy)]bis[2,2-dimethylpentanoic acid](CAS DataBase Reference)
• NIST Chemistry Reference: 5,5'-[2-(1-hydroxypropyl)-1,4-phenylenebis(oxy)]bis[2,2-dimethylpentanoic acid](79521-18-9)
• EPA Substance Registry System: 5,5'-[2-(1-hydroxypropyl)-1,4-phenylenebis(oxy)]bis[2,2-dimethylpentanoic acid](79521-18-9)

Safety Data

• Hazardous Substances Data: 79521-18-9(Hazardous Substances Data)

Upstream product

• 16940-66-2 sodium tetrahydroborate 
• 79521-17-8 dimethyl 5,5'-[[2-(1-oxopropyl)-1,4-phenylene]bis(oxy)]bis[2,2-dimethylpentanoate] 
• 79520-52-8 5-Bromo-2,2-dimethylpentanoic acid,methyl ester 
• 938-46-5 2',5'-dihydroxypropiophenone 
• 79521-06-5 dimethyl 5,5'-[[2-(1-hydroxypropyl)-1,4-phenylene]bis(oxy)]bis[2,2-dimethylpentanoate] 

Downstream Products

• 79521-07-6 methyl 5,5'<2-(1-propenyl)-1,4-phenylenebis(oxy)>bis<2,2-dimethylpentanoate> 

Relevant articles and documents

Phenylenebis(oxy)bis[2,2-dimethylpentanoic acid]s: Agents that elevate high-density lipoproteins

A series of phenylenebis(oxy)bis[2,2-dimethylpentanoic acid]s have been synthesized and evaluated as potential hypolipidemic agents. Compound 18 (CI-924) was found to be the most potent compound in this series. In rats, compound 18 is not only reduced low-density lipoprotein cholesterol but also increased high-density lipoprotein (HDL cholesterol. Comparative studies in rats indicated 18 produced an equal elevation of HDL cholesterol at one-third of the dose required of gemfibrozil. Structure-activity relationships are discussed.