795289-91-7Relevant articles and documents
Total synthesis of apoptolidin
Wehlan, Hermut,Dauber, Mario,Fernaud, M.-Teresa Mujica,Schuppan, Julia,Mahrwald, Rainer,Ziemer, Burkhard,Garcia, M.-Elisa Juarez,Koert, Ulrich
, p. 4597 - 4601 (2004)
A ring-size-selective macrolactonization and the early introduction of the saccharide portions are the main features of a total synthesis of the 20-membered macrolide apoptolidin (see formula), which induces apoptosis in rat glia cells transformed with oncogenes.