80108-14-1 Usage
Description
(1Z)-7-Chloro-3-(3,4-dichlorophenyl)-10-hydroxy-1-([(Z)-3-(4-methyl-1-piperazinyl)propyl]imino)-1,3,4,10-tetrahydro-9(2H)-acridinone is a complex chemical compound that belongs to the acridinone class. It is derived from acridine, a heterocyclic compound with applications in medicinal chemistry. (1Z)-7-Chloro-3-(3,4-dichlorophenyl)-10-hydroxy-1-([(Z)-3-(4-methyl-1piperazinyl)propyl]imino)-1,3,4,10-tetrahydro-9(2H)-acridinone features a unique structure that includes chlorine, hydroxyl, and piperazinyl groups, which may contribute to its potential pharmaceutical properties. Its ability to interact with specific cellular pathways or biomolecules makes it a promising candidate for drug development and medical research.
Uses
Used in Pharmaceutical Development:
(1Z)-7-Chloro-3-(3,4-dichlorophenyl)-10-hydroxy-1-([(Z)-3-(4-methyl-1-piperazinyl)propyl]imino)-1,3,4,10-tetrahydro-9(2H)-acridinone is used as a pharmaceutical candidate due to its potential to target specific cellular pathways or biomolecular interactions. Its unique chemical composition, including chlorine, hydroxyl, and piperazinyl groups, may contribute to its effectiveness in treating certain medical conditions.
Used in Medical Research:
This acridinone compound is also utilized in medical research to explore its potential applications in various therapeutic areas. Its structural features and interactions with cellular pathways make it a valuable tool for understanding disease mechanisms and developing new treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 80108-14-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,0 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80108-14:
(7*8)+(6*0)+(5*1)+(4*0)+(3*8)+(2*1)+(1*4)=91
91 % 10 = 1
So 80108-14-1 is a valid CAS Registry Number.
80108-14-1Relevant articles and documents
Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures
Kesten, Stephen J.,Degnan, Margaret J.,Hung, Jocelyn,McNamara, Dennis J.,Ortwine, Daniel F.,et al.
, p. 3429 - 3447 (2007/10/02)
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.
