805242-49-3

Basic information

• Product Name: Benzene, [(1,1-difluoroethyl)sulfonyl]-
• CAS NO: 805242-49-3
• Molecular Formula: C8H8F2O2S
• Molecular Weight: 206.213
• Mol File: 805242-49-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, [(1,1-difluoroethyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1,1-difluoroethyl)sulfonyl]-(805242-49-3)
• EPA Substance Registry System: Benzene, [(1,1-difluoroethyl)sulfonyl]-(805242-49-3)

Safety Data

• Hazardous Substances Data: 805242-49-3(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 1535-67-7 difluoromethyl phenyl sulfide 
• 1535-65-5 difluoromethyl phenyl sulfone 
• 74-88-4 methyl iodide 

Downstream Products

• 1049104-77-9 (1,1-difluoroethyl)triethylsilane 
• 597-52-4 Triethylsilanol 
• 994-49-0 hexaethyl disiloxane 
• 107-46-0 Hexamethyldisiloxane 
• 10409-06-0 diphenyl disulfone 
• 115134-88-8 (1,1-difluoroethyl)trimethylsilane 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

Synthesis of 1,1-difluoroethylsilanes and their application for the introduction of the 1,1-difluoroethyl group

1,1-Difluoroethysilanes (R3SiCF2CH3, R = Me or Et) were synthesized from 1,1-difluoroethyl phenyl sulfone and chlorosilanes using magnesium metal via reductive 1,1-difluoroethylation. It was confirmed that 1,1-difluoroethylsilanes were effective 1,1-difluoroethylating reagents for carbonyl compounds.

Difluoromethyl phenyl sulfone, a difluoromethylidene equivalent: Use in the synthesis of 1,1-difluoro-1-alkenes

A nucleophilic substitution-elimination reaction strategy in which difluoromethyl phenyl sulfone is used as a selective difluoromethylidene equivalent allows the facile synthesis of 1,1-difluoro-1-alkenes from primary alkyl halides (see scheme).