80708-25-4Relevant articles and documents
5,10-Dihydropyrido-pyrazolo-triazine compounds and application thereof
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Paragraph 0103; 0104; 0105, (2017/08/02)
The invention relates to 5,10-dihydropyrido[2',3':5,6]pyrazolo[2,3-e][1,2,4]triazine compounds shown in general formula I, and their optical activators or racemates or their pharmaceutically acceptable salts, hydrates or solvates, wherein substituents R1,
Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors
Dudash Jr., Joseph,Zhang, Yongzheng,Moore, John B.,Look, Richard,Liang, Yin,Beavers, Mary Pat,Conway, Bruce R.,Rybczynski, Philip J.,Demarest, Keith T.
, p. 4790 - 4793 (2007/10/03)
A series of 3-anilino-quinoxalinones has been identified as a new class of glycogen phosphorylase inhibitors. The lead compound 1 was identified through high throughput screening as well as through pharmacophore-based electronic screening. Modifications were made to the scaffold of 1 to produce novel analogues, some of which are 25 times more potent than the lead compound.
Thiazoloquinoxalin-1,4-diones for treating allergy
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, (2008/06/13)
New triazoloquinoxalin-1,4-diones are described as well as the use thereof as anti-allergenic agents.