80726-52-9

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-3-(methylthio)-4-phenyl-
• CAS NO: 80726-52-9
• Molecular Formula: C15H13NOS
• Molecular Weight: 255.34
• Mol File: 80726-52-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-3-(methylthio)-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-3-(methylthio)-4-phenyl-(80726-52-9)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-3-(methylthio)-4-phenyl-(80726-52-9)

Safety Data

• Hazardous Substances Data: 80726-52-9(Hazardous Substances Data)

Upstream product

• 507-40-4 tert-butylhypochlorite 
• 4455-13-4 methylthioacetic acid ethyl ester 
• 2113-55-5 3-phenylaniline hydrochloride 
• 2243-47-2 3-biphenyl amine 

Downstream Products

• 35523-93-4 4-phenyl-1,3-dihydro-indol-2-one 

Relevant articles and documents

3-methyl-hio-4-(5-, 6-, or 7-)phenylindolindolin-2-ones

This invention relates to novel compounds having the formula: STR1 wherein; R1 is fluoro, chloro, bromo, lower-alkyl or nitro, R2 is lower alkyl, lower alkoxy, fluoro, chloro, bromo, nitro or trifluoromethyl, and m and n are 0-2 with the proviso that when R1 or R2 are tertiary butyl or a sterically hindering lower alkyl radical, m and/or n are 1. These compounds are intermediates in the preparation of 2-aminobiphenylacetic acids, esters and metal salts thereof.

Antiinflammatory Agents. 2. Syntheses and Antiinflammatory Activity of Substituted 2-Aminophenylacetic Acid Derivatives

Several substituted 2-aminophenylacetic acid derivatives were prepared and tested for in vitro prostaglandin synthetase inhibition and for in vivo antiinflammatory activity.The 2-amino substituent is beneficial to potency in the inhibition of prostaglandin synthetase for the 3-phenoxy, 4-phenyl, and 3-benzoyl series, but only 3-benzoyl series shows increased antiinflammatory potency in the in vivo assay.