80866-82-6

Basic information

• Product Name: 5-BROMO-2-METHOXYBENZYL ALCOHOL
• Synonyms: RARECHEM AL BD 0053;5-BROMO-O-ANISYL ALCOHOL;5-BROMO-2-METHOXYBENZYL ALCOHOL;(5-BROMO-2-METHOXY-PHENYL)-METHANOL;4-BROMO-2-(HYDROXYMETHYL)ANISOLE;5-Bromo-2-methoxybenzyl alcohol 98%;5-Bromo-2-methoxybenzyl alcohol,97%;BenzeneMethanol, 5-broMo-2-Methoxy-
• CAS NO: 80866-82-6
• Molecular Formula: C₈H₉BrO₂
• Molecular Weight: 217.06
• EINECS: 279-586-7
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Alcohol;Alcohols;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;C7 to C8;Oxygen Compounds
• Mol File: 80866-82-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 68-71 °C(lit.)
• Boiling Point: 192.5°C (rough estimate)
• Flash Point: 134.9 °C
• Appearance: White to off-white crystalline powder
• Density: 1.4816 (rough estimate)
• Vapor Pressure: 0.000533mmHg at 25°C
• Refractive Index: 1.4930 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BROMO-2-METHOXYBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHOXYBENZYL ALCOHOL(80866-82-6)
• EPA Substance Registry System: 5-BROMO-2-METHOXYBENZYL ALCOHOL(80866-82-6)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 36/37/38-22
• Safety Statements: 37/39-26-24/25
• WGK Germany: 3
• Hazardous Substances Data: 80866-82-6(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powder

InChI:InChI=1/C8H9BrO2/c1-11-8-3-2-7(9)4-6(8)5-10/h2-4,10H,5H2,1H3

Upstream product

• 7017-52-9 4-bromo-2-(chloromethyl)-1-methoxybenzene 
• 2316-64-5 5-bromo-2-hydroxybenzyl alcohol 
• 74-88-4 methyl iodide 
• 1638291-19-6 5-bromo-2-methoxy-N-methyl-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 630050-32-7 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1638287-10-1 5-bromo-2-methoxy-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1711-09-7 3-bromobenzoyl chloride 
• 612-16-8 (2-methoxyphenyl)methanol 
• 25016-01-7 5-bromo-2-methoxybenzaldehyde 

Downstream Products

• 114303-65-0 2-allyl-4-bromo-1-methoxybenzene 
• 68592-15-4 methylhonokiol 
• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 904311-20-2 (2-methoxy-5-(methylthio)phenyl)methanol 
• 1090896-93-7 3-[3-(5-bromo-2-methoxy-benzyl)-2-oxo-2,3-dihydro-benzoimidazol-1-yl]-hexanoic acid 
• 1609560-45-3 tert-butyl 2-methoxy-5-bromobenzoperoxoate 
• 2476-35-9 5-bromo-2-methoxybenzoic acid 
• 1396507-32-6 C₂₄H₃₉⁽¹⁸⁾FN₂O₂Si 
• 1396507-21-3 (S)-N-((1-allylpyrrolidin-2-yl)methyl)-5-(di-tert-butylfluorosilyl)-2-methoxybenzamide 
• 1396506-38-9 5-(di-tert-butylfluorosilyl)-2-methoxybenzoic acid 

Relevant articles and documents

Dehydroxymethyl Bromination of Alkoxybenzyl Alcohols by Using a Hypervalent Iodine Reagent and Lithium Bromide

We describe the dehydroxymethylbromination of alkoxybenzyl alcohol by using a hypervalent iodine reagent and lithium bromide in F 3 CCH 2 OH at room temperature. Selective monobromination or dibromination was possible by adjusting the molar ratios of hypervalent iodine reagent and lithium bromide.

New method of synthesis and biological evaluation of some combretastatin A-4 analogues

A series of novel combretastatin A-4 analogues was synthesized in 36-64% yields by Negishi cross-coupling reaction under mild conditions. The prepared compounds exhibit good cytotoxicity against HBL100 epithelial cell lines (IC50=0.022-10.31 ). Georg Thieme Verlag Stuttgart · New York.

N-bromosuccinimide: A facile reagent for the oxidation of benzylic alcohols to aldehydes

The oxidation of benzylic alcohols to aldehydes using N-bromosuccinimide (NBS) under ambient conditions without use of a transition-metal catalyst has been described. Copyright Taylor & Francis Group, LLC.