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808768-89-0

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808768-89-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 808768-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,8,7,6 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 808768-89:
(8*8)+(7*0)+(6*8)+(5*7)+(4*6)+(3*8)+(2*8)+(1*9)=220
220 % 10 = 0
So 808768-89-0 is a valid CAS Registry Number.

808768-89-0Relevant articles and documents

The synthesis of two potent β-3 adrenergic receptor agonists

Bradley, Paul A.,Lecouturier, Yann C.,Noeureuil, Pierre,Patel, Bhairavi,Wheeler, Simon,Carroll, Robert J.,Moore, Robert,Snow, Jonathan

experimental part, p. 1326 - 1336 (2011/09/20)

This contribution describes the initial preparation of two potent β-3 receptor agonists 1 and 2. Subsequent scale up of these two compounds was required for further evaluation and proceeded via a common key amine intermediate 24. Synthesis of this key intermediate by way of a Ritter reaction was a vital step in the sequence. Enantioselective Noyori hydrogenation reactions gave access to the chiral epoxides necessary to make the target compounds. Chemistry was developed for the selective dehalogenation of the 2-chloropyridyl group in the presence of a sensitive isoxazole unit to provide access to 1.

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