80947-57-5

Basic information

• Product Name: 6-phenylthio-5-formyluracil
• Synonyms: 6-phenylthio-5-formyluracil
• CAS NO: 80947-57-5
• Molecular Weight: 248.262
• Mol File: 80947-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-phenylthio-5-formyluracil(CAS DataBase Reference)
• NIST Chemistry Reference: 6-phenylthio-5-formyluracil(80947-57-5)
• EPA Substance Registry System: 6-phenylthio-5-formyluracil(80947-57-5)

Safety Data

• Hazardous Substances Data: 80947-57-5(Hazardous Substances Data)

Upstream product

• 15422-05-6 6-(phenylthio)pyrimidine-2,4(1H,3H)-dione 
• 108-98-5 thiophenol 

Relevant articles and documents

Synthesis and Properties of 1-Benzothiopyranopyrimidine-2,4-(3H)diones (10-Thia-5-deazaflavins)

Treatment of 6-arylthiouracils with the Vilsmeier reagent (dimethylformamide-phosphorus oxychloride) gave the corresponding 6-arylthio-5-formyluracils, which could alternatively be prepared by the condensation of 6-chloro-5-formyluracils with thiophenols.Dehydrative cyclization of the above 5-formyluracils with polyphosphoric acid gave 1-benzothiopyranopyrimidine-2,4-(3H)diones (10-thia-5-deazaflavins).These 10-thia-5-deazaflavins oxidized alcohols to give the corresponding carbonyl compounds with the aid of strong base, and they were hydrogenated to 1,5-dihydro-10-thia-5-deazaflavins.Treatment of 10-thia-5-deazaflavins with the concentrated aqueous potassium hydroxide led to the exclusive formation of 1,5-dihydro-10-thia-5-deazaflavins and 1,5-dihydro-10-thia-5-deazaflavins-5-ones via intermolecular oxidation-reduction (disproportionation) between initially formed 1,5-dihydro-5-hydroxy-10-thia-5-deazaflavins and unchanged 10-thia-5-deazaflavins.