80965-30-6 Usage
General Description
4-(4-methylpiperidino)pyridine is an organic chemical compound with the molecular formula C11H16N2. It is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. This chemical is a derivative of pyridine, which is a six-membered ring structure containing five carbon atoms and one nitrogen atom. The presence of the methylpiperidino group in the molecule adds a piperidine ring to the pyridine structure, giving it additional functionality and reactivity. 4-(4-methylpiperidino)pyridine is known for its use in various chemical and pharmaceutical processes, making it an important compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 80965-30-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,9,6 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 80965-30:
(7*8)+(6*0)+(5*9)+(4*6)+(3*5)+(2*3)+(1*0)=146
146 % 10 = 6
So 80965-30-6 is a valid CAS Registry Number.
80965-30-6Relevant articles and documents
SELECTIVE INHIBITORS AND ALLOSTERIC ACTIVATORS OF SPHINGOSINE KINASE
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Page/Page column 83-84, (2014/08/19)
Sphingosine 1-phosphate (S1P) is involved in hyper-proliferative diseases, such as cancer and vascular remodeling in pulmonary arterial hypertension. Inhibitors of sphingosine kinase 1 and 2 (SK1 and SK2), which catalyze the synthesis of S1P, may be useful anti- proliferative agents. We have synthesized a series of sphingosine-based inhibitors of SK and SK2. Also provided in this invention are compounds that activate SK1 which can be used in diseases such as fibrosis, where intracellular S1P is anti-fibrotic.
Synthesis of aminopyridines via an unprecedented nucleophilic aromatic substitution of cyanopyridines
Penney, Jonathan M.
, p. 2667 - 2669 (2007/10/03)
The direct reaction of 2- and 4-cyanopyridines with lithium amides affords good yields of the corresponding aminopyridines via displacement of cyanide. Addition of CsF accelerates the reaction and can lead to significantly higher yields.