81-11-8

Basic information

• Product Name: 4,4'-Diamino-2,2'-stilbenedisulfonic acid
• Synonyms: Diaminostilbene-2,2'-disulfonic acid;4,4'-Diaminostilbene-2,2'-disulphonicacid(Amsonicacid);4,4'-Diamino-2,2'-st;Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-aMino-;2,2’-(1,2-ethenediyl)bis[5-amino-benzenesulfonicaci;2,2’-(1,2-ethenediyl)bis[5-amino-Benzenesulfonicacid;2,2’-(1,2-ethenediyl)bis[5-amino-benzenesulfonicacid];2,2’-(1,2-ethylenediyl)bis(5-amino-benzenesulfonicaci
• CAS NO: 81-11-8
• Molecular Formula: C₁₄H₁₄N₂O₆S₂
• Molecular Weight: 370.4
• EINECS: 201-325-2
• Product Categories: Stilbenes;Fluorescent Labels & Indicators;Intermediates of Dyes and Pigments
• Mol File: 81-11-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 300 °C
• Appearance: Cream to yellow-brown/Crystalline Powder
• Density: 1.4732 (rough estimate)
• Vapor Pressure: 1.3hPa at 25℃
• Refractive Index: 1.6510 (estimate)
• Storage Temp.: -20°C Freezer
• PKA: -1.58±0.50(Predicted)
• Water Solubility: <0.1 g/100 mL at 23 oC
• Stability: Stable. Combustible. Incompatible with iron, strong oxidizing agents.
• Merck: 14,595
• BRN: 629516
• CAS DataBase Reference: 4,4'-Diamino-2,2'-stilbenedisulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-Diamino-2,2'-stilbenedisulfonic acid(81-11-8)
• EPA Substance Registry System: 4,4'-Diamino-2,2'-stilbenedisulfonic acid(81-11-8)

Safety Data

• Hazard Codes: C,Xn
• Statements: 34-22-36/37/38-20/21/22
• Safety Statements: 24/25-45-36/37/39-26-22
• RIDADR: UN 2583
• RTECS: WJ6603000
• TSCA: Yes
• Hazardous Substances Data: 81-11-8(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Powder

Uses

Different sources of media describe the Uses of 81-11-8 differently. You can refer to the following data:
1. In manufacture of dyes, bleaching agents.
2. 4,4’-Diaminostilbene-2,2’-disulfonic Acid, 95+% (cas# 81-11-8) is a compound useful in organic synthesis.

General Description

Odorless yellowish microscopic needles or cream-colored powder. pH approximately 4.3 at 30 g/L water (suspension).

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4,4'-Diamino-2,2'-stilbenedisulfonic acid is incompatible with iron. 4,4'-Diamino-2,2'-stilbenedisulfonic acid forms sparingly water-soluble, crystalline salts with many bisquaternary ammonium bases.

Fire Hazard

Flash point data for 4,4'-Diamino-2,2'-stilbenedisulfonic acid are not available; however, 4,4'-Diamino-2,2'-stilbenedisulfonic acid is probably combustible.

Upstream product

• 1211962-72-9 4,4'-dinitrostilbene 2,2'-disulfonic acid 
• 119-72-2 4-nitro-4'-amino-stilbene-2,2'-disulphonic acid 
• 7647-01-0 hydrogenchloride 
• 16473-79-3 4',4'''-dinitro-4,4''-azo-bis-stilbene-2,2'-disulfonic acid 
• 121-03-9 4-nitrotoluene-2-sulfonic acid 
• 7803-57-8 hydrazine hydrate 
• 111-46-6 diethylene glycol 
• 6404-60-0 4,4'-dinitrobibenzyl-2,2'-disulfonic acid 
• 7732-18-5 water 
• 99-99-0 1-methyl-4-nitrobenzene 
• 88-20-0 o-toluenesulfonic acid 
• 108-88-3 toluene 

Downstream Products

• 56682-96-3 5,5'-bis-(4,6-dimethoxy-[1,3,5]triazin-2-ylamino)-2,2'-ethene-1,2-diyl-bis-benzenesulfonic acid 
• 69851-86-1 5-amino-2-formyl-benzenesulfonic acid 
• 5136-34-5 6,6'-(ethane-1,2-diyl)bis(3-aminobenzenesuIfonic acid) 
• 56682-91-8 5,5'-bis-(4-amino-6-chloro-[1,3,5]triazin-2-ylamino)-2,2'-ethene-1,2-diyl-bis-benzenesulfonic acid 
• 26110-34-9 5,5'-bis-(4-chloro-6-methoxy-[1,3,5]triazin-2-ylamino)-2,2'-ethene-1,2-diyl-bis-benzenesulfonic acid 
• 139290-20-3 C₃₄H₂₄Cl₂N₁₀O₁₀S₂ 
• 16013-46-0 5,5'-bis-(4,6-dichloro-[1,3,5]triazin-2-ylamino)-2,2'-ethene-1,2-diyl-bis-benzenesulfonic acid 
• 588-59-0 stilbene 

Relevant articles and documents

Stilbene type compound as well as synthesis method and application thereof

The invention discloses a stilbene type compound as well as a synthesis method and application thereof, wherein the synthesis method comprises the steps: taking an intermediate 2 and an intermediate 4 as initiators, sequentially carrying out Wittig reaction, reduction reaction, amino protection reaction, condensation reaction, deprotection reaction and amidation reaction, and then refining to obtain the stilbene type compound. The synthesis process is high in controllability, used reagents are low in price, and the method is simple and easy to industrialize. The stilbene type compound can be used as a medicine for resisting tumors and viruses and treating fungal infection and cardiovascular and cerebrovascular diseases.

Nitrogen doped carbon supported iron catalysts for highly selective production of 4,4′-diamino-2,2′-stilbenedisulfonic acid

Nitrogen doped carbon supported iron catalysts were prepared from pyrolysis of a multidentate nitrogen ligand iron complex supported on chitosan at different temperature, and showed good performances in the reduction of 4,4′-dinitrostilbene-2,2′-disulfonic acid (DNS acid) to 4,4′-diamino-2,2′-stilbenedisulfonic acid (DSD acid) with hydrazine hydrate (N2H4·H2O) as reductant. Characterization results revealed that the iron is mainly present in the form of Fe2O3 and metallic iron nanoparticles. The doped N atoms functionalized as anchoring sites to stabilize iron nanoparticles, which endows the catalysts with excellent activity and superior reusability.

Preparation method of 4,4'-diamino diphenylethene-disulfonic acid

The invention discloses a preparation method of 4,4'-diamino diphenylethene-disulfonic acid. 4,4'-binitro diphenylethene-disulfonic acid or 4,4'-binitro diphenylethene-disulfonate serves as a raw material, the raw material and a supported catalyst are co-dispersed in a solvent, and 4,4'-diamino diphenylethene-disulfonic acid is prepared through a hydrogenation reaction. Based on the total mass of the supported catalyst, active ingredients in the supported catalyst comprise, by mass, 0.1-10% of platinum, 0-5% of ruthenium and 0-5% of iridium, wherein the mass fraction of ruthenium and the mass fraction of iridium cannot be 0 at the same time. According to the preparation method of 4,4'-diamino diphenylethene-disulfonic acid, the high-activity and high-selectivity supported catalyst is adopted, and the produced product reaches the China chemical industry standard HG/T 2279-2011.