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81004-54-8

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  • 3H-Imidazo[2,1-i]purine,3-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-b-D-erythro-pentofuranosyl]-

    Cas No: 81004-54-8

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  • 3H-Imidazo[2,1-i]purine,3-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-b-D-erythro-pentofuranosyl]-

    Cas No: 81004-54-8

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81004-54-8 Usage

Chemical structure

1,N(6)-etheno-2'-deoxyadenosine 5'-triphosphate is a modified form of deoxyadenosine triphosphate (dATP) with an etheno group attached to the N(6) position of the adenine base.

Induction

The modification can be induced by exposure to certain chemical and physical agents.

DNA adducts

The presence of 1,N(6)-etheno-2'-deoxyadenosine 5'-triphosphate in the cell can lead to the formation of DNA adducts.

Genetic mutations

The formation of DNA adducts can cause genetic mutations.

Carcinogenesis

The genetic mutations can potentially contribute to carcinogenesis.

Disruption of DNA replication and repair

The presence of 1,N(6)-etheno-2'-deoxyadenosine 5'-triphosphate in the cell can disrupt normal DNA replication and repair processes.

Genomic instability

The disruption of DNA replication and repair processes can lead to genomic instability.

Mutagenic and genotoxic compound

1,N(6)-etheno-2'-deoxyadenosine 5'-triphosphate is considered a mutagenic and genotoxic compound.

Cellular integrity and function

The compound can have harmful effects on cellular integrity and function.

Substrate for DNA polymerases

Studies have shown that this modified nucleotide can serve as a substrate for DNA polymerases.

Incorporation into DNA

The modified nucleotide can be incorporated into DNA.

Potential for mutagenic events

The incorporation of the modified nucleotide into DNA can lead to the potential for mutagenic events.

Check Digit Verification of cas no

The CAS Registry Mumber 81004-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,0,0 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81004-54:
(7*8)+(6*1)+(5*0)+(4*0)+(3*4)+(2*5)+(1*4)=88
88 % 10 = 8
So 81004-54-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N5O12P3/c18-7-3-9(17-6-14-10-11-13-1-2-16(11)5-15-12(10)17)27-8(7)4-26-31(22,23)29-32(24,25)28-30(19,20)21/h1-2,5-9,18H,3-4H2,(H,22,23)(H,24,25)(H2,19,20,21)/t7-,8+,9+/m0/s1

81004-54-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-imidazo[2,1-f]purin-3-yloxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate

1.2 Other means of identification

Product number -
Other names Etheno deoxyadenosine triphosphate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81004-54-8 SDS

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