81120-73-2

Basic information

• Product Name: patellamide A
• Synonyms: patellamide A
• CAS NO: 81120-73-2
• Molecular Formula: C35H50N8O6S2
• Molecular Weight: 742.9515
• Mol File: 81120-73-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 995°C at 760 mmHg
• Flash Point: 555.5°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: patellamide A(CAS DataBase Reference)
• NIST Chemistry Reference: patellamide A(81120-73-2)
• EPA Substance Registry System: patellamide A(81120-73-2)

Safety Data

• Hazardous Substances Data: 81120-73-2(Hazardous Substances Data)

Usage

Description

Patellamide A is a cyclic peptide compound isolated from the ascidian Lissoclinum patella, belonging to the patellamide family known for their potent biological activities. It exhibits cytotoxic and antifungal properties, making it a potentially valuable compound for pharmaceutical and medicinal applications.

Uses

Used in Pharmaceutical Industry:
Patellamide A is used as a lead compound for drug development due to its cytotoxic and antifungal properties, offering potential applications in the creation of new therapeutic agents.
Used in Medicinal Applications:
Patellamide A is used as a bioactive compound for its potential to treat various conditions, leveraging its cytotoxic and antifungal properties to combat infections and other diseases.
Used in Natural Products Research:
Patellamide A is used as a subject of study in natural products research to understand its chemical and biological properties, contributing to the advancement of drug discovery and development.
Used in Chemical Synthesis and Modification Studies:
Patellamide A is used as a compound of interest in the synthesis and modification of related compounds, with the aim of enhancing their properties and potential applications in medicine and pharmaceuticals.

InChI:InChI=1/C35H50N8O6S2/c1-10-17(7)25-32-36-20(12-48-32)28(44)39-23(15(3)4)34-37-22(14-50-34)30(46)42-26(18(8)11-2)33-43-27(19(9)49-33)31(47)40-24(16(5)6)35-38-21(13-51-35)29(45)41-25/h13-20,23-27H,10-12H2,1-9H3,(H,39,44)(H,40,47)(H,41,45)(H,42,46)/t17-,18-,19+,20-,23+,24+,25-,26-,27-/m0/s1

Upstream product

• 103929-30-2 C₃₅H₅₁ClN₈O₆S₂ 
• 100803-71-2 Boc-L-Ile-L-aThr-D-(val)Thz-OMe 
• 100803-69-8 Boc-D-(val)Thz-OMe 
• 103929-32-4 D-(val)Thz-OMe 
• 103929-29-9 Boc-L-Ile-L-aThr-D-(val)Thz-L-Ile-L-Ser-D-(val)Thz-OMe 
• 103945-78-4 (4S,7S,10R,17S,20S,23R)-4,17-Di-sec-butyl-7-((S)-1-hydroxy-ethyl)-20-hydroxymethyl-10,23-diisopropyl-12,25-dithia-3,6,9,16,19,22,27,28-octaaza-tricyclo[22.2.1.1^11,14]octacosa-1⁽²⁶⁾,11⁽²⁸⁾,13,24⁽²⁷⁾-tetraene-2,5,8,15,18,21-hexaone 
• 103929-28-8 H-L-Ile-L-Ser-D-(val)Thz-OMe*HCl 
• 106402-36-2 H-L-aThr-D-(val)Thz-OMe 
• 103929-26-6 Boc-L-Ile-L-Ser-D-(val)Thz-OMe 
• 103929-34-6 H-L-Ser-D-(val)Thz-OMe*HCl 
• 103929-27-7 Boc-L-Ile-L-aThr-D-(val)Thz-OH 
• 103929-24-4 Boc-L-aThr-D-(val)Thz-OMe 
• 103929-25-5 Boc-(S)-Ser-(R)-Val-Thz-OMe 

Relevant articles and documents

NEW METHODS AND REAGENTS IN ORGANIC SYNTHESIS. 58. A SYNTHESIS OF PATELLAMIDE A, A CYTOTOXIC CYCLIC PEPTIDE FROM A TUNICATE. REVISION OF ITS PROPOSED STRUCTURE

The real structure of patellamide A, a cytotoxic lipophilic cyclic peptide from a marine tunicate, has been unambiguously determined by the synthesis of both its proposed and revised structures.