81428-86-6

Basic information

• Product Name: 1H-2-Benzopyran-1-one, 3,4-dihydro-3-(3-methoxyphenyl)-
• CAS NO: 81428-86-6
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Mol File: 81428-86-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran-1-one, 3,4-dihydro-3-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-1-one, 3,4-dihydro-3-(3-methoxyphenyl)-(81428-86-6)
• EPA Substance Registry System: 1H-2-Benzopyran-1-one, 3,4-dihydro-3-(3-methoxyphenyl)-(81428-86-6)

Safety Data

• Hazardous Substances Data: 81428-86-6(Hazardous Substances Data)

Upstream product

• 34040-62-5 o-(chloromethyl)benzoic acid methyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 496-14-0 1,3-dihydroisobenzofuran 
• 257882-73-8 2-[2-oxo-2-(3'-methoxyphenyl)ethyl]benzoic acid 
• 1711-05-3 m-anisoyl chloride 
• 89-51-0 Homophthalic acid 
• 56383-91-6 3-(3-methoxyphenyl)-1H-isochromen-1-one 
• 860812-75-5 2-[2-hydroxy-2-(3-methoxy-phenyl)-ethyl]-benzoic acid 
• 180068-10-4 3-(3'-methoxyphenyl)isochromane 
• 180068-09-1 2-(2-Hydroxymethyl-phenyl)-1-(3-methoxy-phenyl)-ethanol 
• 93012-04-5 2?(3-methoxystyryl)benzoic acid 

Relevant articles and documents

Metal-Free Addition of Benzyl Halides to Aldehydes Using Super Electron Donors: Access to 3,4-Dihydroisocoumarins and 1,2-Diarylethanols

We report here the intermolecular metal-free addition reaction of functionalized benzyl halides to aldehydes using a super electron donor (SED). The metal-free and mild conditions allowed the formation of 3,4-dihydroisocoumarins and 1,2-diarylethanols with unprecedented functional group tolerance.

Oxidation of 3-arylisochromans by dimethyldioxirane. An easy route to substituted 3-arylisocoumarins

The selective oxidation of the two different benzylethereal position of 3-arylisochromans by dimethyldioxirane as a function of different substituents on the aromatic rings was studied. The easy oxidation of these compounds was exploited for a new easy ac

Ortho-Lithiated Tertiary Benzamides. Chain Extension via o-Toluamide Anion and General Synthesis of Isocoumarins Including Hydrangenol and Phyllodulcin

Lithiation of N,N-diethyl-2-methylbenzamide (2a) followed by condensation with aromatic aldehydes and basic hydrolysis leads to 3-aryl-3,4-dihydroisocoumarins 4 in modest overall yields.Adoption of this methodology to N,N-dimethyl-2-methyl-6-methoxybenzamide (7b) provides isocoumarins 9a and 9b which by selective demethylation procedures yields hydrangenol (10a) and phyllodulcin (10c), naturally occurring isocoumarins of pharmacological interest.A one-pot, abbreviated procedure for the preparation of both 9a and 9b starting with N,N-Dimethyl-2-methoxybenzamide (6c) is also described.