815610-30-1Relevant articles and documents
Application of a double Mannich reaction using bis(aminol) ethers in the synthesis of AE ring analogues of methyl lycaconitine
Brocke, Constanze,Brimble, Margaret A.,Lin, Diana S.-H.,McLeod, Malcolm D.
, p. 2359 - 2363 (2004)
An efficient method for the construction of azabicyclo[3.3.1]nonanes and azabicyclo[3.2.1]octanes is reported via double Mannich reaction of cyclic ketoesters with bis(aminol) ethers. This method is applied to the synthesis of AE ring analogues of methyl lycaconitine.