81946-79-4Relevant articles and documents
6- and 6,6-disubstituted-3-substituted-1-azabicyclo(3.2.0)hept-2-en-7-one-2-carboxylic acids
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, (2008/06/13)
Disclosed are 6- and 6,6-disubstituted-3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R1 and R2 are, inter alia, independently selected from the group consisting of hydrogen (both are not hydrog
Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid
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, (2008/06/13)
Disclosed is a process for preparing 3-substituted-thio-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acids (I) STR1 wherein X is a leaving group such as chloro, bromo, tosyl, mesyl or the like; and R8 is, inter alia, sel
Simple and Condensed β-Lactams. Part 5. The Synthesis of some (5RS,6SR)-2-(Formylaminoethylthio)-6-(2-methyl-1,3-dioxolan-2-yl)carbapenem-3-carboxylic Acid Derivatives and Related Compounds
Fetter, Jozsef,Lempert, Karoly,Gizur, Tibor,Nyitrai, Jozsef,Kajtar-Peredy, Maria,et al.
, p. 221 - 228 (2007/10/02)
Starting with the 4-oxoazetidine-2-carboxylic acids (3a) and (3b), methods for the synthesis of derivatives of the racemic carbapenem-3-carboxylic acid (2), an analogue of the potent antibiotic thienamycin have been developed.The synthetic steps included