82091-12-1

Basic information

• Product Name: Benzoic acid, 2,2'-[carbonylbis(oxy)]bis-, dimethyl ester
• CAS NO: 82091-12-1
• Molecular Formula: C17H14O7
• Molecular Weight: 330.294
• Mol File: 82091-12-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,2'-[carbonylbis(oxy)]bis-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,2'-[carbonylbis(oxy)]bis-, dimethyl ester(82091-12-1)
• EPA Substance Registry System: Benzoic acid, 2,2'-[carbonylbis(oxy)]bis-, dimethyl ester(82091-12-1)

Safety Data

• Hazardous Substances Data: 82091-12-1(Hazardous Substances Data)

Upstream product

• 31349-66-3 methyl 2-((phenethylcarbamoyl)oxy)benzoate 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 119-36-8 methyl salicylate 
• 75-44-5 phosgene 

Downstream Products

• 124-38-9 carbon dioxide 
• 31680-22-5 2,2'-Oxybisbenzoesaeure-dimethylester 
• 119-36-8 methyl salicylate 
• 31349-66-3 methyl 2-((phenethylcarbamoyl)oxy)benzoate 
• 22001-35-0 methyl 2-((dimethylcarbamoyl)oxy)benzoate 

Relevant articles and documents

HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS

The present invention provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof; (I) which are inhibitors of WDR5. The present invention also provides pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compounds.

Tandem buildup of complexity of aromatic molecules through multiple successive electrophile generation in one pot, controlled by varying the reaction temperature

While some sequential electrophilic aromatic substitution reactions, known as tandem/domino/cascade reactions, have been reported for the construction of aromatic single skeletons, one of the most interesting and challenging possibilities remains the one-pot build-up of a complex aromatic molecule from multiple starting components, i.e., ultimately multi-component electrophilic aromatic substitution reactions. In this work, we show how tuning of the leaving group ability of phenolate derivatives from carbamates and esters provides a way to successively generate multiple unmasked electrophiles in a controlled manner in one pot, simply by varying the temperature. Here, we demonstrate the autonomous formation of up to three bonds in one pot and formation of two bonds arising from a three-component electrophilic aromatic substitution reaction. This result provides a proof-of-concept of our strategy applicable for the self-directed construction of complex aromatic structures from multiple simple molecules, which can be a potential avenue to realize multi-component electrophilic aromatic substitution reactions.

METHOD OF PREPARING ESTER-SUBSTITUTED DIARYL CARBONATES

An improved method for the preparation of ester-substituted diaryl carbonates prepared by reacting phosgene with recycle streams of ester-substituted phenols from reaction processes using a tetraalkyl ammonium hydroxide catalyst, a tetraalkyl phosphonium