82176-57-6

Basic information

• Product Name: α-bromo-β-methylstyrene
• Synonyms: α-bromo-β-methylstyrene
• CAS NO: 82176-57-6
• Molecular Weight: 197.074
• Mol File: 82176-57-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: α-bromo-β-methylstyrene(CAS DataBase Reference)
• NIST Chemistry Reference: α-bromo-β-methylstyrene(82176-57-6)
• EPA Substance Registry System: α-bromo-β-methylstyrene(82176-57-6)

Safety Data

• Hazardous Substances Data: 82176-57-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 637-50-3 1-phenylpropene 
• 93-55-0 1-phenyl-propan-1-one 
• 673-32-5 1-Phenylprop-1-yne 
• 10602-62-7 dihydrogen erythro-(1,2-dibromo-1-phenylpropyl)phosphonate 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 75-65-0 tert-butyl alcohol 
• 108-95-2 phenol 
• 64-17-5 ethanol 
• 67-63-0 isopropyl alcohol 
• 600-36-2 2,4-dimethyl-3-pentanol 
• 73083-32-6 α-Lithium-α,α-dibromtoluol 
• 75-03-6 ethyl iodide 
• 56484-51-6 2-ethyl-2-phenyl-1,3-benzodioxole 

Downstream Products

• 637-50-3 1-phenylpropene 
• 768-00-3 (E)-2-phenyl-2-butene 
• 1609102-41-1 (E)-1-nitro-2-(1-phenylprop-1-enyl)benzene 
• 4403-15-0 hexa-2,4-diene-3,4-diyldibenzene 
• 123902-49-8 ((E)-1-phenyl-2-methylvinyl)(chloromethyl)dimethylsilane 
• 96430-43-2 (E)-(2-phenyl-3-methylallyl)dimethylchlorosilane 
• 96430-44-3 (Z)-(2-phenyl-3-methylallyl)dimethylchlorosilane 
• 96430-42-1 (1-phenyl-2-methylcyclopropyl)dimethylchlorosilane 

Relevant articles and documents

Enantioselective Nickel-Catalyzed Alkyne-Azide Cycloaddition by Dynamic Kinetic Resolution

The triazole heterocycle has been widely adopted as an isostere for the amide bond. Many native amides are α-chiral, being derived from amino acids. This makes α-N-chiral triazoles attractive building blocks. This report describes the first enantioselective triazole synthesis that proceeds via nickel-catalyzed alkyne-azide cycloaddition (NiAAC). This dynamic kinetic resolution is enabled by a spontaneous [3,3]-sigmatropic rearrangement of the allylic azide. The 1,4,5-trisubstituted triazole products, derived from internal alkynes, are complementary to those commonly obtained by the related CuAAC reaction. Initial mechanistic experiments indicate that the NiAAC reaction proceeds through a monometallic Ni complex, which is distinct from the CuAAC manifold.

Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of β-SCF3 Carbonyl Compounds with α-Quaternary Carbon Center

A new and modular electrophilic trifluoromethylthiolation/semipinacol rearrangement of allylic silyl ethers has been developed under mild conditions. This approach allows the formation of a number of β-SCF3 carbonyl compounds with a cyclic and all-carbon quaternary center framework in moderate to good yields. It should be noted that this achievement is a metal-free process and just requires the use of simple acetyl chloride as an acidic promoter. Additionally, an interesting H-migration in competition with aryl-migration process was revealed.

ANODIC FUNCTIONALIZATION OF OLEFINS IN ALCOHOLS IN THE PRESENCE OF HALIDE SALTS

Electrolysis of conjugated, unbranched arylolefins in the presence of alkali metal halides in alcohols affords 1-aryl-2-bromoketals in 60-90percent yields.Under these conditions, 2-methyl-1-phenylprop-1-ene is converted into 1-bromo-2-methyl-1-phenylprop-1-ene in 80percent yield, and arylolefins with no benzylidene hydrogens give 1-aryl-1-alkoxy-2-bromoalkanes.