82317-85-9 Usage
Description
(R)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid is a complex chemical compound featuring a propanoic acid backbone, an amino acid functional group, and a tert-butoxycarbonyl protecting group on the amino group. It also includes a phenyl ring with three methoxy groups, contributing to its intricate structure. (R)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid's unique features suggest potential pharmacological properties, making it a promising candidate for research in medicinal chemistry and pharmacology.
Uses
Used in Pharmaceutical Industry:
(R)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid is used as a potential pharmaceutical compound for its unique structure and properties. The presence of both an amino acid and a phenyl group, along with the tert-butoxycarbonyl protecting group, may offer novel therapeutic applications in the development of new drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (R)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid serves as a subject of interest for its complex structure and potential pharmacological properties. Researchers may explore its interactions with biological targets and its potential as a lead compound in the development of new therapeutic agents.
Used in Pharmacology Studies:
(R)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid is used as a research subject in pharmacology to investigate its effects on biological systems. Its unique structure may provide insights into new mechanisms of action and contribute to the understanding of drug-receptor interactions and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 82317-85-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,1 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 82317-85:
(7*8)+(6*2)+(5*3)+(4*1)+(3*7)+(2*8)+(1*5)=129
129 % 10 = 9
So 82317-85-9 is a valid CAS Registry Number.
82317-85-9Relevant articles and documents
Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer–Hexamer Assembly
Lakemeyer, Markus,Bertosin, Eva,M?ller, Friederike,Balogh, Dóra,Strasser, Ralf,Dietz, Hendrik,Sieber, Stephan A.
supporting information, p. 7127 - 7132 (2019/04/27)
The proteolytic complex ClpXP is fundamental to bacterial homeostasis and pathogenesis. Because of its conformational flexibility, the development of potent ClpXP inhibitors is challenging, and novel tools to decipher its intricate regulation are urgently needed. Herein, we present amino acid based phenyl esters as molecular probes to study the activity and oligomerization of the ClpXP complex of S. aureus. Systematic screening of (R)- and (S)-amino acids led to compounds showing potent inhibition, as well as stimulation of ClpXP-mediated proteolysis. Substoichiometric binding of probes arrested ClpXP in an unprecedented heptamer–hexamer assembly, in which the two heptameric ClpP rings are dissociated from each other. At the same time, the affinity between ClpX and ClpP increased, leading to inhibition of both enzymes. This conformational arrest is beneficial for the consolidated shutdown of ClpXP, as well as for the study of the oligomeric state during its catalytic cycle.
