824960-02-3 Usage
Description
JWH-182 is a potent synthetic cannabinoid (CB) that selectively activates the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM. Its effects in cells and animals are currently unknown.
Uses
Used in Pharmaceutical Research:
JWH-182 is used as a research compound for studying the effects and mechanisms of action of synthetic cannabinoids on the CB1 and CB2 receptors. This helps in understanding the potential therapeutic applications and side effects associated with these compounds.
Used in Drug Development:
JWH-182 serves as a lead compound in the development of new drugs targeting the CB1 and CB2 receptors. Its high affinity and selectivity for these receptors make it a valuable tool in designing more effective and safer medications for various conditions.
Used in Toxicological Studies:
JWH-182 is utilized in toxicological research to evaluate the safety and potential risks associated with synthetic cannabinoids. This helps in determining the appropriate dosages, administration routes, and potential side effects of these compounds in humans.
Note: The uses mentioned above are based on the general applications of synthetic cannabinoids and may not be specific to JWH-182. Further research and development are required to fully understand the potential uses and implications of JWH-182 in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 824960-02-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,4,9,6 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 824960-02:
(8*8)+(7*2)+(6*4)+(5*9)+(4*6)+(3*0)+(2*0)+(1*2)=173
173 % 10 = 3
So 824960-02-3 is a valid CAS Registry Number.
824960-02-3Relevant articles and documents
CB2-selective cannabinoid analogues
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Page 24, (2010/02/10)
Cannabinoid analogues that exhibit specificity for the CB2 cannabinoid receptor are provided. The analogues are 1-methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Δ8-tetrahydrocannabinols and 1-alkyl-3(1-naphthoyl)indoles. The compounds are useful for the treatment of pain (especially pain resulting from inflammation) and cancer (especially glioma tumors).
