824961-53-7Relevant articles and documents
Preparation method of pyrrole aldehyde compound
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Paragraph 0059-0062; 0091-0094, (2020/08/02)
The invention discloses a preparation method of a pyrrole aldehyde compound, and relates to the technical field of compound preparation. According to the method, initial materials are mixed and react,wherein the initial materials comprise a substituted pyridine quaternary ammonium salt, an iodine source, an alkali and water, the structural formula of the substituted pyridine quaternary ammonium salt is defined in the specification, the substituent R is at the ortho-position and/or meta-position of a nitrogen atom, R is alkyl, aryl, heteroaryl or halogen, and the substituent R3 is alkyl or benzyl. The method is simple to operate, raw materials are easy to obtain, the chemical selectivity is good, few byproducts are produced, a substrate can be converted into various other useful molecules,the method has high practicability compared with the existing preparation of the pyrrole aldehyde compound, and the yield can reach 86% at most.
