82668-32-4

Basic information

• Product Name: 2-N,N-di-n-propylamino-4,7-dimethoxyindan
• Synonyms: 2-N,N-di-n-propylamino-4,7-dimethoxyindan;2-(Dipropylamino)-4,7-dimethoxyindane;2,3-Dihydro-4,7-dimethoxy-N,N-dipropyl-1H-inden-2-amine;RDS-127
• CAS NO: 82668-32-4
• Molecular Formula: C17H27NO2
• Molecular Weight: 277.4018
• Mol File: 82668-32-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 409.5°Cat760mmHg
• Flash Point: 135.5°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 6.48E-07mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: 2-N,N-di-n-propylamino-4,7-dimethoxyindan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-N,N-di-n-propylamino-4,7-dimethoxyindan(82668-32-4)
• EPA Substance Registry System: 2-N,N-di-n-propylamino-4,7-dimethoxyindan(82668-32-4)

Safety Data

• Hazardous Substances Data: 82668-32-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H27NO2/c1-5-9-18(10-6-2)13-11-14-15(12-13)17(20-4)8-7-16(14)19-3/h7-8,13H,5-6,9-12H2,1-4H3

Upstream product

• 81664-68-8 4,7-Dimethoxy-indan-2-carboxylic acid ethyl ester 
• 52428-09-8 4,7-dimethoxyindan-1-one 
• 81664-67-7 2-carbethoxy-2,3-dihydro-4,7-dimethoxy-1H-inden-1-one 
• 81664-69-9 2,3-dihydro-4,7-dimethoxy-1H-indene-2-carboxylic acid 
• 79381-08-1 2,3-dihydro-4,7-dimethoxy-1H-inden-2-amine 
• 802294-64-0 propionic acid 

Relevant articles and documents

2-Amino-4,7-dimethoxyindan Derivatives: Synthesis and Assessment of Dopaminergic and Cardiovascular Actions

N-Alkylated derivatives of 2-amino-4,7-dimethoxyindan were prepared for evaluation of central and peripheral dopaminergic activity using biochemical and behavioral tests in the rat and cardiovascular responses in the cat. 2-(Di-n-propylamino)-4,7-dimethoxyindan (4e) demonstrated equal activity with apomorphine to activate peripheral presynaptic dopamine receptors.Central pre- and postsynaptic dopamine receptors were also activated with 4e.In contrast to the intense long-acting sympathomimetic actions previously reported for the 2-amino-5,8-dimethoxytetralins, these compounds produced weak, transient effects in heart rate and blood pressure.The majority of 2-amino-4,7-dimethoxyindan derivatives tested are weak or inactive pre- and postsynaptic dopamine receptor agonists.