82673-70-9

Basic information

• Product Name: 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one
• Synonyms: 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one
• CAS NO: 82673-70-9
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.1879
• Mol File: 82673-70-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one(82673-70-9)
• EPA Substance Registry System: 5-Methoxy-3,4-dihydro-1,7-naphthyridin-2(1H)-one(82673-70-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 82673-70-9(Hazardous Substances Data)

Upstream product

• 82673-66-3 ethyl 3-(3-methoxy-5-pivaloylamino-4-pyridyl)acrylate 
• 77903-31-2 4-Formyl-3-methoxy-5-(pivaloylamino)pyridine 
• 82673-69-6 ethyl 3-(3-methoxy-5-pivaloylamino-4-pyridyl)propionate 

Relevant articles and documents

Synthetic Application of Lithiation Reactions: A Convenient Synthesis of 3,4-Dihydro-5-hydroxycarbostyril, 1,2,3,4-Tetrahydro-5-hydroxy-2-oxo-1,7-naphthyridine, and Methyl 3-Methoxypyridine-4-carboxylate

3,4-Dihydro-5-hydroxycarbostyril (3), a key intermediate for a clinically used β-receptor blocking agent (1), and its 7-aza analog (4) were prepared by an acid-catalyzed cyclization of the N-pivaloylamino-esters (17 and 19), which were obtained by using o