82782-33-0

Basic information

• Product Name: 5-(4-methoxyphenyl)-3-oxopentanoic acid,ethyl ester
• Synonyms: 5-(4-methoxyphenyl)-3-oxopentanoic acid,ethyl ester
• CAS NO: 82782-33-0
• Molecular Weight: 250.295
• Mol File: 82782-33-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-(4-methoxyphenyl)-3-oxopentanoic acid,ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)-3-oxopentanoic acid,ethyl ester(82782-33-0)
• EPA Substance Registry System: 5-(4-methoxyphenyl)-3-oxopentanoic acid,ethyl ester(82782-33-0)

Safety Data

• Hazardous Substances Data: 82782-33-0(Hazardous Substances Data)

Upstream product

• 136637-32-6 5-[3-(4-methoxyphenyl)propanoyl]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 64-17-5 ethanol 
• 15893-42-2 3-(4-methoxyphenyl)propionyl chloride 
• 141-97-9 ethyl acetoacetate 
• 104-20-1 4-(4-methoxyphenyl)-2-butanone 
• 105-58-8 Diethyl carbonate 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 603998-94-3 ethyl (2Z)-3-amino-5-(4-methoxyphenyl)-2-pentenoate 

Relevant articles and documents

Intramolecular [1 + 4 + 1] cycloaddition: Establishment of the method

Structurally complex and physiologically active natural products often include bicyclic and polycyclic ring systems having defined relative and absolute configuration. Approaches that allow the construction of more than one carbocyclic ring at a time have proven valuable, in particular those that allow at the same time the control of an array of new stereogenic centers. One of the most general and most widely used protocols has been the intramolecular Diels-Alder [4 + 2] cycloaddition, in which a single stereogenic center between the diene and the dienophile can control the relative and absolute configuration of the product. We report a two-step [1 + 4 + 1] procedure for bicyclic and polycyclic construction, based on the cyclization of an ω-dienyl ketone. This is complementary to, and will likely be as useful as, the intramolecular Diels-Alder cycloaddition.

2-mercaproimidazole dopamine-β-hydroxylase inhibitors

Potent dopamine-β-hydroxylase inhibitors having the Formula STR1 that are useful to inhibit dopamine-β-hydroxylase activity, pharmaceutial compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-β-hydroxylase act

Method of using phenyl-alkylene-2-pyridyl derivatives to increase cardiac contractility in a mammal

Compounds of the formulae: STR1 wherein, Z and Y are each alkylene or oxy-alkylene containing one to about five carbon atoms in the principal chain or said alkylene substituted with OH, alkanoyloxy, alkoxy, mercapto or alkylmercapto; each of R1, R2 and R3 is independently H, alkyl, aryl, halo, alkoxy, alkenyloxy, alkylsulfinyl, alkylsulfonyl, alkylmercapto, cyano, carboxy, carbalkoxy, carboxamido, sulfamoyl, trifluoromethyl, hydroxy, hydroxyalkyl, acyloxy, alkylamino, sulfonylamino, or acylamino; or R1 and R2, when taken together, form a methylenedioxy or --O--CO--O--; Ar is heteroaryl, cycloalkyl or STR2 wherein, R1, R2 and R3 are as hereindescribed; and R is H, alkyl, cycloalkyl, aryl, aralkyl, alkenyl, alkynyl, carboalkoxy, or CONR4 R5 wherein each of R4 and R5 is H or alkyl; wherein the total number of carbon atoms in each hydrocarbyl group is up to 10; and STR3 wherein, each of R1 and R2 is independently H, alkyl, aryl, halo, alkoxy, alkenyloxy, alkylsulfinyl, alkylsulfonyl, alkylmercapto, cyano, carboxy, carbalkoxy, carboxamido, sulfamoyl, trifluoromethyl, hydroxy, hydroxyalkyl, acyloxy, alkylamino, sulfonylamino, or acylamino; or R1 and R2, when taken together, form a methylenedioxy, or --O--CO--O--; R6 is H, alkyl, aryl, halo, alkoxy, alkenyloxy, alkylsulfonyl, alkylmercapto, cyano, carboxy, carbalkoxy, carboxamido, sulfamoyl, trifluoromethyl, hydroxy, hydroxyalkyl, acyloxy, alkylamino, sulfonylamino or acylamino; wherein the total number of carbon atoms in each hydrocarbyl group is up to 10; and acid addition salts thereof have selective cardiotonic, antihypertensive and antiallergic activity.