82801-81-8

Basic information

• Product Name: 3,4-Methylenedioxy-N-ethylamphetamine
• Synonyms: 3,4-methylenedioxyethamphetamine;(+/-)-3,4-METHYLENEDIOXYETHYLAMPHETAMINE;AURORA KA-7747;1,3-Benzodioxole-5-ethanamine, N-ethyl-alpha-methyl-, hydrochloride;3,4-METHYLENDIOXYETHYLAMPHETAMIN;3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE;3,4-METHYLENDIOXYETHYLAMPHETAMIN, >99% (HPLC);N-Ethyl-1-(3,4-methylenedioxyphenyl)-2-propylamine
• CAS NO: 82801-81-8
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.27
• EINECS: 200-659-6
• Mol File: 82801-81-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 140-145 °C
• Boiling Point: bp0.2 85-95°
• Flash Point: 9℃
• Appearance: white crystalline powder
• Density: 1.078 g/cm³
• Vapor Pressure: 0.00117mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: 2-8°C
• PKA: 10.34±0.19(Predicted)
• CAS DataBase Reference: 3,4-Methylenedioxy-N-ethylamphetamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Methylenedioxy-N-ethylamphetamine(82801-81-8)
• EPA Substance Registry System: 3,4-Methylenedioxy-N-ethylamphetamine(82801-81-8)

Safety Data

• Hazard Codes: Xi,T,F
• Statements: 36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• Hazardous Substances Data: 82801-81-8(Hazardous Substances Data)

Usage

Uses

Methylenedioxyethamphetamine is a illegal psychoactive substance.

Hazard

Human systemic effects.

InChI:InChI=1/C12H17NO2/c1-3-13-9(2)6-10-4-5-11-12(7-10)15-8-14-11/h4-5,7,9,13H,3,6,8H2,1-2H3

Upstream product

• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 557-66-4 ethanamine hydrochloride 
• 75-04-7 ethylamine 
• 36209-71-9 N-[1-methyl-2-(3,4-methylenedioxyphenyl)ethyl]acetamide 
• 5438-41-5 5-(2-nitroprop-1-enyl)benzo[d][1,3]dioxole 
• 4764-17-4 3,4-methylenedioxyamphetamine 

Downstream Products

• 4764-17-4 3,4-methylenedioxyamphetamine 

Relevant articles and documents

Centrally active N-substituted analogs of 3,4-methylenedioxyphenylisopropylamine (3,4-methylenedioxyamphetamine)

The known central nervous system activity of 3,4-methylenedioxyphenylisopropylamine and its N-methyl homolog prompted the synthesis of a series of analogs with substituents on the nitrogen atom. Most of these analogs (R = alkyl, alkenyl, hydroxy, alkoxy, and alkoxyalkyl) were prepared by the reductive alkylation of 3,4-methylenedioxyphenylacetone with the appropriate amine and sodium cyanoborohydride. Hindered isomers were synthesized indirectly. Measurements of their pharmacological activity in several animal assays and in human subjects indicated that the central activity decreased with the increasing bulk of the N-substituent.